Excitatory Amino Acid Transporter 2
"Excitatory Amino Acid Transporter 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glutamate plasma membrane transporter protein found in ASTROCYTES and in the LIVER.
Descriptor ID |
D027342
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MeSH Number(s) |
D12.776.157.530.200.249.500.500.750 D12.776.157.530.450.625.147.750 D12.776.157.530.562.374.781.750 D12.776.157.530.937.250.500.750 D12.776.543.585.200.249.500.500.750 D12.776.543.585.450.625.147.750 D12.776.543.585.562.374.781.750 D12.776.543.585.937.250.500.750
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Concept/Terms |
Excitatory Amino Acid Transporter 2- Excitatory Amino Acid Transporter 2
- EAAT2 Neurotransmitter Transporter
- Neurotransmitter Transporter, EAAT2
- EAAT-2 Excitatory Amino Acid Transporter
- EAAT 2 Excitatory Amino Acid Transporter
- GLT-1 Transport Protein
- GLT 1 Transport Protein
- Transport Protein, GLT-1
- SLC1A2 Transporter
- Transporter, SLC1A2
- GluT-1 Glutamate Transporter
- GluT 1 Glutamate Transporter
- Glutamate Transporter, GluT-1
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Below are MeSH descriptors whose meaning is more general than "Excitatory Amino Acid Transporter 2".
Below are MeSH descriptors whose meaning is more specific than "Excitatory Amino Acid Transporter 2".
This graph shows the total number of publications written about "Excitatory Amino Acid Transporter 2" by people in this website by year, and whether "Excitatory Amino Acid Transporter 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 0 | 2 | 2 |
2013 | 1 | 1 | 2 |
2014 | 2 | 1 | 3 |
2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Excitatory Amino Acid Transporter 2" by people in Profiles.
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Griffin WC, Haun HL, Ramachandra VS, Knackstedt LA, Mulholland PJ, Becker HC. Effects of ceftriaxone on ethanol drinking and GLT-1 expression in ethanol dependence and relapse drinking. Alcohol. 2021 05; 92:1-9.
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Farrand AQ, Gregory RA, Bäckman CM, Helke KL, Boger HA. Altered glutamate release in the dorsal striatum of the MitoPark mouse model of Parkinson's disease. Brain Res. 2016 11 15; 1651:88-94.
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Roberts-Wolfe DJ, Kalivas PW. Glutamate Transporter GLT-1 as a Therapeutic Target for Substance Use Disorders. CNS Neurol Disord Drug Targets. 2015; 14(6):745-56.
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Farrand AQ, Gregory RA, Scofield MD, Helke KL, Boger HA. Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice. Neurobiol Aging. 2015 Mar; 36(3):1569-76.
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Reissner KJ, Gipson CD, Tran PK, Knackstedt LA, Scofield MD, Kalivas PW. Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement. Addict Biol. 2015 Mar; 20(2):316-23.
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Scofield MD, Kalivas PW. Astrocytic dysfunction and addiction: consequences of impaired glutamate homeostasis. Neuroscientist. 2014 Dec; 20(6):610-22.
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Reissner KJ, Brown RM, Spencer S, Tran PK, Thomas CA, Kalivas PW. Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism. Neuropsychopharmacology. 2014 Jan; 39(2):499-506.
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Gipson CD, Reissner KJ, Kupchik YM, Smith AC, Stankeviciute N, Hensley-Simon ME, Kalivas PW. Reinstatement of nicotine seeking is mediated by glutamatergic plasticity. Proc Natl Acad Sci U S A. 2013 May 28; 110(22):9124-9.
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Reissner KJ, Kalivas PW. Using glutamate homeostasis as a target for treating addictive disorders. Behav Pharmacol. 2010 Sep; 21(5-6):514-22.
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Knackstedt LA, Melendez RI, Kalivas PW. Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking. Biol Psychiatry. 2010 Jan 01; 67(1):81-4.