"PDZ Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.
- PDZ Domains
- Domain, PDZ
- Domains, PDZ
- PDZ Domain
- PDZ Interaction Domains
- Domain, PDZ Interaction
- Domains, PDZ Interaction
- Interaction Domain, PDZ
- Interaction Domains, PDZ
- PDZ Interaction Domain
- PSD95-DLG-ZO1 Domains
- Domain, PSD95-DLG-ZO1
- Domains, PSD95-DLG-ZO1
- PSD95 DLG ZO1 Domains
- PSD95-DLG-ZO1 Domain
- DLG Homology Repeats Domains
- GLGF Repeats Domains
- Domain, GLGF Repeats
- Domains, GLGF Repeats
- GLGF Repeats Domain
- Repeats Domain, GLGF
- Repeats Domains, GLGF
- DHR Domains
- DHR Domain
- Domain, DHR
- Domains, DHR
Below are MeSH descriptors whose meaning is more general than "PDZ Domains".
Below are MeSH descriptors whose meaning is more specific than "PDZ Domains".
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Below are the most recent publications written about "PDZ Domains" by people in Profiles.
Identifying weak interdomain interactions that stabilize the supertertiary structure of the N-terminal tandem PDZ domains of PSD-95. Nat Commun. 2018 09 13; 9(1):3724.
Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS). J Biol Chem. 2012 Mar 16; 287(12):9441-53.
The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins. J Biol Chem. 2008 Sep 05; 283(36):24718-28.