Joe B Blumer

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressP.O. Box MSC 509
BSB 313D
173 Ashley Ave.
Phone843-792-3552
Fax843-792-2475
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    Collapse Biography 
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    2009 - 2014R01 GM086510 "AGS4 in G-protein Signal Processing", Medical University of South Carolina

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Elmansi AM, Eisa NH, Periyasamy-Thandavan S, Kondrikova G, Kondrikov D, Calkins MM, Aguilar-P?rez A, Chen J, Johnson M, Shi XM, Reitman C, McGee-Lawrence ME, Crawford KS, Dwinell MB, Volkman BF, Blumer JB, Luttrell LM, McCorvy JD, Hill WD, Elmansi AM, Eisa NH, Periyasamy-Thandavan S, Kondrikova G, Kondrikov D, Calkins MM, Aguilar-P?rez A, Chen J, Johnson M, Shi XM, Reitman C, McGee-Lawrence ME, Crawford KS, Dwinell MB, Volkman BF, Blumer JB, Luttrell LM, McCorvy JD, Hill WD. DPP4-Truncated CXCL12 Alters CXCR4/ACKR3 Signaling, Osteogenic Cell Differentiation, Migration, and Senescence. ACS Pharmacol Transl Sci. 2023 Jan 13; 6(1):22-39. PMID: 36659961; PMCID: PMC9844133.
      Citations:    
    2. Blumer JB, Kruidering M, Brandl K, McPhail B, Simmons MA. American Society for Pharmacology and Experimental Therapeutics Division for Pharmacology Education at EB2022-Meeting report. Pharmacol Res Perspect. 2022 Oct; 10(5):e01014. PMID: 36210650; PMCID: PMC9549069.
      Citations:    Fields:    Translation:Humans
    3. Quesnelle KM, Zaveri NT, Schneid SD, Blumer JB, Szarek JL, Kruidering M, Lee MW, Quesnelle KM, Zaveri NT, Schneid SD, Blumer JB, Szarek JL, Kruidering M, Lee MW. Design of a foundational sciences curriculum: Applying the ICAP framework to pharmacology education in integrated medical curricula. Pharmacol Res Perspect. 2021 05; 9(3):e00762. PMID: 33974344; PMCID: PMC8112301.
      Citations:    
    4. Quesnelle KM, Zaveri NT, Schneid SD, Blumer JB, Szarek JL, Kruidering M, Lee MW, Quesnelle KM, Zaveri NT, Schneid SD, Blumer JB, Szarek JL, Kruidering M, Lee MW. The importance of collaboratively designing pharmacology education programs. Pharmacol Res Perspect. 2021 05; 9(3):e00773. PMID: 33974347; PMCID: PMC8112302.
      Citations:    
    5. Adekoya TO, Smith N, Aladeniyi T, Blumer JB, Chen XL, Richardson RM, Adekoya TO, Smith N, Aladeniyi T, Blumer JB, Chen XL, Richardson RM. Activator of G protein signaling 3 modulates prostate tumor development and progression. Carcinogenesis. 2019 12 31; 40(12):1504-1513. PMID: 31215992; PMCID: PMC7346714.
      Citations:    
    6. Vural A, Nabar NR, Hwang IY, Sohn S, Park C, Karlsson MCI, Blumer JB, Kehrl JH, Vural A, Nabar NR, Hwang IY, Sohn S, Park C, Karlsson MCI, Blumer JB, Kehrl JH. Gai2 Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination. J Immunol. 2019 03 01; 202(5):1510-1520. PMID: 30683698; PMCID: PMC6382563.
      Citations:    
    7. Robichaux WG, Branham-O'Connor M, Hwang IY, Vural A, Kehrl JH, Blumer JB, Robichaux WG, Branham-O'Connor M, Hwang IY, Vural A, Kehrl JH, Blumer JB. Regulation of Chemokine Signal Integration by Activator of G-Protein Signaling 4 (AGS4). J Pharmacol Exp Ther. 2017 03; 360(3):424-433. PMID: 28062526; PMCID: PMC5325072.
      Citations:    
    8. Vural A, Al-Khodor S, Cheung GY, Shi CS, Srinivasan L, McQuiston TJ, Hwang IY, Yeh AJ, Blumer JB, Briken V, Williamson PR, Otto M, Fraser ID, Kehrl JH, Vural A, Al-Khodor S, Cheung GY, Shi CS, Srinivasan L, McQuiston TJ, Hwang IY, Yeh AJ, Blumer JB, Briken V, Williamson PR, Otto M, Fraser ID, Kehrl JH. Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. J Immunol. 2016 Jan 15; 196(2):846-56. PMID: 26667172; PMCID: PMC4811337.
      Citations:    
    9. Rasmussen SA, Kwon M, Pressly JD, Blumer JB, Regner KR, Park F, Rasmussen SA, Kwon M, Pressly JD, Blumer JB, Regner KR, Park F. Activator of G-protein Signaling 3 Controls Renal Epithelial Cell Survival and ERK5 Activation. J Mol Signal. 2015 Nov 27; 10:6. PMID: 27096004; PMCID: PMC4831271.
      Citations:    
    10. Robichaux WG, Oner SS, Lanier SM, Blumer JB, Robichaux WG, Oner SS, Lanier SM, Blumer JB. Direct Coupling of a Seven-Transmembrane-Span Receptor to a Gai G-Protein Regulatory Motif Complex. Mol Pharmacol. 2015 Aug; 88(2):231-7. PMID: 25972449; PMCID: PMC4518091.
      Citations:    
    11. Brown NE, Blumer JB, Hepler JR, Brown NE, Blumer JB, Hepler JR. Bioluminescence resonance energy transfer to detect protein-protein interactions in live cells. Methods Mol Biol. 2015; 1278:457-65. PMID: 25859969; PMCID: PMC4682348.
      Citations:    
    12. Zhang J, Ye ZW, Gao P, Reyes L, Jones EE, Branham-O'Connor M, Blumer JB, Drake RR, Manevich Y, Townsend DM, Tew KD, Zhang J, Ye ZW, Gao P, Reyes L, Jones EE, Branham-O'Connor M, Blumer JB, Drake RR, Manevich Y, Townsend DM, Tew KD. Glutathione S-transferase P influences redox and migration pathways in bone marrow. PLoS One. 2014; 9(9):e107478. PMID: 25216273; PMCID: PMC4162606.
      Citations:    
    13. Branham-O'Connor M, Robichaux WG, Zhang XK, Cho H, Kehrl JH, Lanier SM, Blumer JB, Branham-O'Connor M, Robichaux WG, Zhang XK, Cho H, Kehrl JH, Lanier SM, Blumer JB. Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3). J Biol Chem. 2014 Apr 11; 289(15):10738-10747. PMID: 24573680; PMCID: PMC4036190.
      Citations:    
    14. Bradley A, Zheng H, Ziebarth A, Sakati W, Branham-O'Connor M, Blumer JB, Liu Y, Kistner-Griffin E, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Landen CN, Eblen ST, Bradley A, Zheng H, Ziebarth A, Sakati W, Branham-O'Connor M, Blumer JB, Liu Y, Kistner-Griffin E, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Landen CN, Eblen ST. EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer. Carcinogenesis. 2014 May; 35(5):1100-9. PMID: 24379240; PMCID: PMC4004201.
      Citations:    
    15. Blumer JB, Lanier SM, Blumer JB, Lanier SM. Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad. Mol Pharmacol. 2014 Mar; 85(3):388-96. PMID: 24302560; PMCID: PMC3935153.
      Citations:    
    16. Vural A, McQuiston TJ, Blumer JB, Park C, Hwang IY, Williams-Bey Y, Shi CS, Ma DZ, Kehrl JH, Vural A, McQuiston TJ, Blumer JB, Park C, Hwang IY, Williams-Bey Y, Shi CS, Ma DZ, Kehrl JH. Normal autophagic activity in macrophages from mice lacking Gai3, AGS3, or RGS19. PLoS One. 2013; 8(11):e81886. PMID: 24312373; PMCID: PMC3842979.
      Citations:    
    17. Oner SS, Blumer JB, Lanier SM, Oner SS, Blumer JB, Lanier SM. Group II activators of G-protein signaling: monitoring the interaction of Ga with the G-protein regulatory motif in the intact cell. Methods Enzymol. 2013; 522:153-67. PMID: 23374185.
      Citations:    
    18. Vellano CP, Brown NE, Blumer JB, Hepler JR, Vellano CP, Brown NE, Blumer JB, Hepler JR. Assembly and function of the regulator of G protein signaling 14 (RGS14)?H-Ras signaling complex in live cells are regulated by Gai1 and Gai-linked G protein-coupled receptors. J Biol Chem. 2013 Feb 01; 288(5):3620-31. PMID: 23250758; PMCID: PMC3561580.
      Citations:    
    19. Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE, Avner ED, Blumer JB, Staruschenko A, Park F, Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE, Avner ED, Blumer JB, Staruschenko A, Park F. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52):21462-7. PMID: 23236168; PMCID: PMC3535663.
      Citations:    
    20. Oner SS, Maher EM, Gabay M, Tall GG, Blumer JB, Lanier SM, Oner SS, Maher EM, Gabay M, Tall GG, Blumer JB, Lanier SM. Regulation of the G-protein regulatory-Gai signaling complex by nonreceptor guanine nucleotide exchange factors. J Biol Chem. 2013 Feb 01; 288(5):3003-15. PMID: 23212907; PMCID: PMC3561525.
      Citations:    
    21. Orr RK, Hoehn JL, Col NF, Vellano CP, Maher EM, Hepler JR, Blumer JB. G protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14?Gai1 complex in live cells. J Biol Chem. 2011 Nov 04; 286(44):38659-38669. PMID: 21880739; PMCID: PMC3207400.
      Citations:    
    22. Blumer JB, Oner SS, Lanier SM, Blumer JB, Oner SS, Lanier SM. Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. Acta Physiol (Oxf). 2012 Feb; 204(2):202-18. PMID: 21615707.
      Citations:    
    23. Reissner KJ, Uys JD, Schwacke JH, Comte-Walters S, Rutherford-Bethard JL, Dunn TE, Blumer JB, Schey KL, Kalivas PW, Reissner KJ, Uys JD, Schwacke JH, Comte-Walters S, Rutherford-Bethard JL, Dunn TE, Blumer JB, Schey KL, Kalivas PW. AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis. J Neurosci. 2011 Apr 13; 31(15):5648-58. PMID: 21490206; PMCID: PMC3595532.
      Citations:    
    24. Orr RK, Hoehn JL, Col NF, Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE, Park F. Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASEB J. 2011 Jun; 25(6):1844-55. PMID: 21343176; PMCID: PMC3101034.
      Citations:    
    25. Chan P, Gabay M, Wright FA, Kan W, Oner SS, Lanier SM, Smrcka AV, Blumer JB, Tall GG, Chan P, Gabay M, Wright FA, Kan W, Oner SS, Lanier SM, Smrcka AV, Blumer JB, Tall GG. Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf). J Biol Chem. 2011 Jan 28; 286(4):2625-35. PMID: 21115479; PMCID: PMC3024758.
      Citations:    
    26. Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM, Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM. Regulation of the AGS3?G{alpha}i signaling complex by a seven-transmembrane span receptor. J Biol Chem. 2010 Oct 29; 285(44):33949-58. PMID: 20716524; PMCID: PMC2962495.
      Citations:    
    27. Nadella R, Blumer JB, Jia G, Kwon M, Akbulut T, Qian F, Sedlic F, Wakatsuki T, Sweeney WE, Wilson PD, Lanier SM, Park F, Nadella R, Blumer JB, Jia G, Kwon M, Akbulut T, Qian F, Sedlic F, Wakatsuki T, Sweeney WE, Wilson PD, Lanier SM, Park F. Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD. J Am Soc Nephrol. 2010 Aug; 21(8):1275-80. PMID: 20488951; PMCID: PMC2938587.
      Citations:    
    28. Oner SS, Maher EM, Breton B, Bouvier M, Blumer JB, Oner SS, Maher EM, Breton B, Bouvier M, Blumer JB. Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai. J Biol Chem. 2010 Jul 02; 285(27):20588-94. PMID: 20452976; PMCID: PMC2898320.
      Citations:    
    29. Vural A, Oner S, An N, Simon V, Ma D, Blumer JB, Lanier SM, Vural A, Oner S, An N, Simon V, Ma D, Blumer JB, Lanier SM. Distribution of activator of G-protein signaling 3 within the aggresomal pathway: role of specific residues in the tetratricopeptide repeat domain and differential regulation by the AGS3 binding partners Gi(alpha) and mammalian inscuteable. Mol Cell Biol. 2010 Mar; 30(6):1528-40. PMID: 20065032; PMCID: PMC2832490.
      Citations:    
    30. Raji B, Dansault A, Vieira V, de la Houssaye G, Lacassagne E, Kobetz A, Arbogast L, Dufier JL, Blumer JB, Menasche M, Abitbol M, Raji B, Dansault A, Vieira V, de la Houssaye G, Lacassagne E, Kobetz A, Arbogast L, Dufier JL, Blumer JB, Menasche M, Abitbol M. Analysis of partner of inscuteable (mPins) expression in the developing mouse eye. Mol Vis. 2008; 14:2575-96. PMID: 19122831; PMCID: PMC2613078.
      Citations:    
    31. An N, Blumer JB, Bernard ML, Lanier SM, An N, Blumer JB, Bernard ML, Lanier SM. The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins. J Biol Chem. 2008 Sep 05; 283(36):24718-28. PMID: 18566450; PMCID: PMC2529004.
      Citations:    
    32. Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM, Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM. Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function. Endocrinology. 2008 Aug; 149(8):3842-9. PMID: 18450958; PMCID: PMC2488243.
      Citations:    
    33. Blumer JB, Smrcka AV, Lanier SM, Blumer JB, Smrcka AV, Lanier SM. Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling. Pharmacol Ther. 2007 Mar; 113(3):488-506. PMID: 17240454; PMCID: PMC1978177.
      Citations:    
    34. Blumer JB, Kuriyama R, Gettys TW, Lanier SM, Blumer JB, Kuriyama R, Gettys TW, Lanier SM. The G-protein regulatory (GPR) motif-containing Leu-Gly-Asn-enriched protein (LGN) and Gialpha3 influence cortical positioning of the mitotic spindle poles at metaphase in symmetrically dividing mammalian cells. Eur J Cell Biol. 2006 Dec; 85(12):1233-40. PMID: 17000024.
      Citations:    
    35. Song KS, Peterson YK, Freidman A, Blumer JB, Sato M, Lanier SM, Song KS, Peterson YK, Freidman A, Blumer JB, Sato M, Lanier SM. Identification and characterization of a G-protein regulatory motif in WAVE1. FEBS Lett. 2006 Apr 03; 580(8):1993-8. PMID: 16530190.
      Citations:    
    36. Sato M, Blumer JB, Simon V, Lanier SM, Sato M, Blumer JB, Simon V, Lanier SM. Accessory proteins for G proteins: partners in signaling. Annu Rev Pharmacol Toxicol. 2006; 46:151-87. PMID: 16402902.
      Citations:    
    37. Sans N, Wang PY, Du Q, Petralia RS, Wang YX, Nakka S, Blumer JB, Macara IG, Wenthold RJ, Sans N, Wang PY, Du Q, Petralia RS, Wang YX, Nakka S, Blumer JB, Macara IG, Wenthold RJ. mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. Nat Cell Biol. 2005 Dec; 7(12):1179-90. PMID: 16299499.
      Citations:    
    38. Blumer JB, Cismowski MJ, Sato M, Lanier SM, Blumer JB, Cismowski MJ, Sato M, Lanier SM. AGS proteins: receptor-independent activators of G-protein signaling. Trends Pharmacol Sci. 2005 Sep; 26(9):470-6. PMID: 16084602.
      Citations:    
    39. Nair KS, Mendez A, Blumer JB, Rosenzweig DH, Slepak VZ, Nair KS, Mendez A, Blumer JB, Rosenzweig DH, Slepak VZ. The presence of a Leu-Gly-Asn repeat-enriched protein (LGN), a putative binding partner of transducin, in ROD photoreceptors. Invest Ophthalmol Vis Sci. 2005 Jan; 46(1):383-9. PMID: 15623799.
      Citations:    
    40. Cao X, Cismowski MJ, Sato M, Blumer JB, Lanier SM, Cao X, Cismowski MJ, Sato M, Blumer JB, Lanier SM. Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha. J Biol Chem. 2004 Jun 25; 279(26):27567-74. PMID: 15096500.
      Citations:    
    41. Blumer JB, Bernard ML, Peterson YK, Nezu J, Chung P, Dunican DJ, Knoblich JA, Lanier SM, Blumer JB, Bernard ML, Peterson YK, Nezu J, Chung P, Dunican DJ, Knoblich JA, Lanier SM. Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha. J Biol Chem. 2003 Jun 27; 278(26):23217-20. PMID: 12719437.
      Citations: 25     Fields:    Translation:AnimalsCells
    42. Blumer JB, Lanier SM, Blumer JB, Lanier SM. Accessory proteins for G protein-signaling systems: activators of G protein signaling and other nonreceptor proteins influencing the activation state of G proteins. Recept Channels. 2003; 9(3):195-204. PMID: 12775339.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
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