Receptors, Bradykinin

"Receptors, Bradykinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface receptors that bind BRADYKININ and related KININS with high affinity and trigger intracellular changes which influence the behavior of cells. The identified receptor types (B-1 and B-2, or BK-1 and BK-2) recognize endogenous KALLIDIN; t-kinins; and certain bradykinin fragments as well as bradykinin itself.

Descriptor ID	D018002
MeSH Number(s)	D12.776.543.750.695.080 D12.776.543.750.720.600.220 D12.776.543.750.750.555.220
Concept/Terms	Receptors, Bradykinin Receptors, Bradykinin Bradykinin Receptor Receptor, Bradykinin Bradykinin Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Bradykinin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Bradykinin [D12.776.543.750.695.080]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Neuropeptide [D12.776.543.750.720.600]
Receptors, Bradykinin [D12.776.543.750.720.600.220]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Neuropeptide [D12.776.543.750.750.555]
Receptors, Bradykinin [D12.776.543.750.750.555.220]

Below are MeSH descriptors whose meaning is related to "Receptors, Bradykinin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Bradykinin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Bradykinin" by people in this website by year, and whether "Receptors, Bradykinin" was a major or minor topic of these publications.

Bar chart showing 26 publications over 11 distinct years, with a maximum of 5 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	3	0	3
1996	3	2	5
1997	2	0	2
1998	2	0	2
1999	1	1	2
2000	2	0	2
2001	3	0	3
2002	2	1	3
2003	1	1	2
2013	0	1	1
2018	1	0	1

Below are the most recent publications written about "Receptors, Bradykinin" by people in Profiles.

Nokkari A, Abou-El-Hassan H, Mechref Y, Mondello S, Kindy MS, Jaffa AA, Kobeissy F. Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms. Prog Neurobiol. 2018 Jun - Aug; 165-167:26-50.

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Magerl M, Bader M, Gompel A, Joseph K, Kaplan AP, Kojda G, Renné T, Wirth M, Maurer M, Church MK. Bradykinin in health and disease: proceedings of the Bradykinin Symposium 2012, Berlin 23-24 August 2012. Inflamm Res. 2014 Mar; 63(3):173-8.

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Privitera PJ, Beckstead RM, Yates P, Walgren R. Autoradiographic localization of [125I-Tyr0]bradykinin binding sites in brains of Wistar-Kyoto and spontaneously hypertensive rats. Cell Mol Neurobiol. 2003 Oct; 23(4-5):805-15.

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Mukhin YV, Garnovsky EA, Ullian ME, Garnovskaya MN. Bradykinin B2 receptor activates extracellular signal-regulated protein kinase in mIMCD-3 cells via epidermal growth factor receptor transactivation. J Pharmacol Exp Ther. 2003 Mar; 304(3):968-77.

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Christopher J, Jaffa AA. Diabetes modulates the expression of glomerular kinin receptors. Int Immunopharmacol. 2002 Dec; 2(13-14):1771-9.

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Ni A, Yin H, Agata J, Yang Z, Chao L, Chao J. Overexpression of kinin B1 receptors induces hypertensive response to des-Arg9-bradykinin and susceptibility to inflammation. J Biol Chem. 2003 Jan 03; 278(1):219-25.

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Kennedy KJ, Orwig KS, Dix TA, Christopher J, Jaffa AA. Synthesis and analysis of potent, more lipophilic derivatives of the bradykinin B2 receptor antagonist peptide Hoe 140. J Pept Res. 2002 Apr; 59(4):139-48.

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Christopher J, Velarde V, Jaffa AA. Induction of B(1)-kinin receptors in vascular smooth muscle cells: cellular mechanisms of map kinase activation. Hypertension. 2001 Sep; 38(3 Pt 2):602-5.

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Christopher J, Velarde V, Zhang D, Mayfield D, Mayfield RK, Jaffa AA. Regulation of B(2)-kinin receptors by glucose in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2001 Apr; 280(4):H1537-46.

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Mukhin YV, Vlasova T, Jaffa AA, Collinsworth G, Bell JL, Tholanikunnel BG, Pettus T, Fitzgibbon W, Ploth DW, Raymond JR, Garnovskaya MN. Bradykinin B2 receptors activate Na+/H+ exchange in mIMCD-3 cells via Janus kinase 2 and Ca2+/calmodulin. J Biol Chem. 2001 May 18; 276(20):17339-46.

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