"Serpins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
| Descriptor ID |
D015843
|
| MeSH Number(s) |
D12.644.861 D12.776.872 D27.505.519.389.745.800.675
|
| Concept/Terms |
Serpins- Serpins
- Serpin Protease Inhibitors
- Inhibitors, Serpin Protease
- Protease Inhibitors, Serpin
- Serpin Peptidase Inhibitors
- Inhibitors, Serpin Peptidase
- Peptidase Inhibitors, Serpin
|
Below are MeSH descriptors whose meaning is more general than "Serpins".
Below are MeSH descriptors whose meaning is more specific than "Serpins".
This graph shows the total number of publications written about "Serpins" by people in this website by year, and whether "Serpins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 3 | 0 | 3 |
| 1996 | 3 | 1 | 4 |
| 1997 | 7 | 0 | 7 |
| 1998 | 2 | 1 | 3 |
| 1999 | 3 | 1 | 4 |
| 2000 | 4 | 0 | 4 |
| 2001 | 3 | 0 | 3 |
| 2002 | 2 | 0 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 3 | 1 | 4 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 1 | 5 |
| 2009 | 3 | 0 | 3 |
| 2010 | 4 | 0 | 4 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 4 | 1 | 5 |
| 2014 | 4 | 0 | 4 |
| 2015 | 4 | 0 | 4 |
| 2016 | 3 | 1 | 4 |
| 2017 | 6 | 0 | 6 |
| 2018 | 3 | 0 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Serpins" by people in Profiles.
-
Protective role of kallistatin in renal fibrosis via modulation of Wnt/?-catenin signaling. Clin Sci (Lond). 2021 02 12; 135(3):429-446.
-
Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease. Biosci Rep. 2020 01 31; 40(1).
-
S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients. Sci Rep. 2019 09 24; 9(1):13792.
-
Serum pigment epithelium-derived factor: Relationships with cardiovascular events, renal dysfunction, and mortality in the Veterans Affairs Diabetes Trial (VADT) cohort. J Diabetes Complications. 2019 10; 33(10):107410.
-
Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. Oxid Med Cell Longev. 2018; 2018:4138560.
-
Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice. J Am Heart Assoc. 2018 11 06; 7(21):e009562.
-
Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway. J Cell Mol Med. 2018 09; 22(9):4387-4398.
-
Opposing Effects of Oxygen Regulation on Kallistatin Expression: Kallistatin as a Novel Mediator of Oxygen-Induced HIF-1-eNOS-NO Pathway. Oxid Med Cell Longev. 2017; 2017:5262958.
-
Kallistatin: double-edged role in angiogenesis, apoptosis and oxidative stress. Biol Chem. 2017 11 27; 398(12):1309-1317.
-
Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. Oxid Med Cell Longev. 2017; 2017:5025610.