"Tissue Kallikreins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A family of trypsin-like SERINE ENDOPEPTIDASES that are expressed in a variety of cell types including human prostate epithelial cells. They are formed from tissue prokallikrein by action with TRYPSIN. They are highly similar to PROSTATE-SPECIFIC ANTIGEN.
    
			
			
				
				
					
						| Descriptor ID | D020840 | 
					
						| MeSH Number(s) | D08.811.277.656.300.760.442.875 D08.811.277.656.959.350.442.875 D23.101.140.870 | 
					
						| Concept/Terms | Tissue KallikreinsTissue KallikreinsKallikreins, TissueHuman Glandular KallikreinsGlandular Kallikreins, HumanKallikreins, Human GlandularTissue KallikreinKallikrein, TissueGlandular KallikreinKallikrein, Glandular
 Human Glandular Kallikrein 1Human Glandular Kallikrein 1Urinary KallikreinKallikrein, UrinaryKallikrein 1Pancreatic KallikreinKallikrein, PancreatichK1 KallikreinKallikrein, hK1Glandular Kallikrein-1Glandular Kallikrein 1Kallikrein-1, Glandular
 Human Glandular Kallikrein 2Human Glandular Kallikrein 2Prostate Specific KallikreinKallikrein, Prostate SpecificSpecific Kallikrein, ProstateKallikrein 2hK2 KallikreinKallikrein, hK2
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				Below are MeSH descriptors whose meaning is more general than "Tissue Kallikreins".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Tissue Kallikreins".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Tissue Kallikreins" by people in this website by year, and whether "Tissue Kallikreins" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
click here. 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1996 | 0 | 2 | 2 | 
| 1997 | 0 | 4 | 4 | 
| 1998 | 0 | 1 | 1 | 
| 1999 | 3 | 2 | 5 | 
| 2000 | 5 | 0 | 5 | 
| 2001 | 1 | 0 | 1 | 
| 2002 | 1 | 1 | 2 | 
| 2003 | 1 | 1 | 2 | 
| 2004 | 2 | 0 | 2 | 
| 2005 | 1 | 0 | 1 | 
| 2006 | 6 | 0 | 6 | 
| 2007 | 2 | 0 | 2 | 
| 2008 | 5 | 0 | 5 | 
| 2009 | 1 | 0 | 1 | 
| 2010 | 3 | 0 | 3 | 
| 2012 | 2 | 0 | 2 | 
| 2013 | 3 | 0 | 3 | 
| 2014 | 1 | 0 | 1 | 
| 2015 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Tissue Kallikreins" by people in Profiles.
						
					
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								Kallistatin ameliorates influenza virus pathogenesis by inhibition of kallikrein-related peptidase 1-mediated cleavage of viral hemagglutinin. Antimicrob Agents Chemother. 2015 Sep; 59(9):5619-30. 
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								Tissue kallikrein-kinin therapy in hypertension and organ damage. Prog Drug Res. 2014; 69:37-57. 
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								Tissue kallikrein-modified mesenchymal stem cells provide enhanced protection against ischemic cardiac injury after myocardial infarction. Circ J. 2013; 77(8):2134-44. 
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								Tissue kallikrein is related to the severity of coronary artery disease. Clin Chim Acta. 2013 Aug 23; 423:90-8. 
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								Tissue kallikrein-modified human endothelial progenitor cell implantation improves cardiac function via enhanced activation of akt and increased angiogenesis. Lab Invest. 2013 May; 93(5):577-91. 
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								Tissue kallikrein activation of the epithelial Na channel. Am J Physiol Renal Physiol. 2012 Aug 15; 303(4):F540-50. 
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								Tissue kallikrein promotes cardiac neovascularization by enhancing endothelial progenitor cell functional capacity. Hum Gene Ther. 2012 Aug; 23(8):859-70. 
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								Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway. Biol Chem. 2010 Jul; 391(7):803-12. 
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								Tissue kallikrein in cardiovascular, cerebrovascular and renal diseases and skin wound healing. Biol Chem. 2010 Apr; 391(4):345-55. 
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								Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation. Am J Physiol Renal Physiol. 2010 Apr; 298(4):F1033-40.