"Integrin alpha2beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.
- Integrin alpha2beta1
- alpha2beta1, Integrin
- VLA 2
- Glycoprotein Ia-IIa
- Glycoprotein Ia IIa
- Very Late Antigen-2
- Late Antigen-2, Very
- Very Late Antigen 2
- CD49b CD29
- Platelet Membrane Glycoprotein Heterodimer Ia-IIa
- Platelet Membrane Glycoprotein Heterodimer Ia IIa
Below are MeSH descriptors whose meaning is more general than "Integrin alpha2beta1".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha2beta1".
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Below are the most recent publications written about "Integrin alpha2beta1" by people in Profiles.
Endothelium-derived Netrin-4 supports pancreatic epithelial cell adhesion and differentiation through integrins a2?1 and a3?1. PLoS One. 2011; 6(7):e22750.
Collagen binding alpha2beta1 and alpha1beta1 integrins play contrasting roles in regulation of Ets-1 expression in human liver myofibroblasts. Mol Cell Biochem. 2006 Jan; 282(1-2):89-99.