"Integrin alpha5beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin found in FIBROBLASTS; PLATELETS; MONOCYTES, and LYMPHOCYTES. Integrin alpha5beta1 is the classical receptor for FIBRONECTIN, but it also functions as a receptor for LAMININ and several other EXTRACELLULAR MATRIX PROTEINS.
| Descriptor ID |
D039081
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| MeSH Number(s) |
D12.776.395.550.625.379 D12.776.543.550.625.379 D12.776.543.750.705.408.530.750 D12.776.543.750.705.408.850.349 D12.776.543.750.705.675.460 D12.776.543.750.705.876.374
|
| Concept/Terms |
Integrin alpha5beta1- Integrin alpha5beta1
- alpha5beta1, Integrin
- Integrin alpha-5 beta-1
- Integrin alpha 5 beta 1
- alpha-5 beta-1, Integrin
- beta-1, Integrin alpha-5
- Platelet Glycoprotein Ic-IIa
- Glycoprotein Ic-IIa, Platelet
- Ic-IIa, Platelet Glycoprotein
- Platelet Glycoprotein Ic IIa
- VLA-5
- VLA-5 Receptors
- VLA 5 Receptors
- Fibronectin Receptor
- Receptor, Fibronectin
- Receptors, VLA-5
- Receptors, VLA 5
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha5beta1".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha5beta1".
This graph shows the total number of publications written about "Integrin alpha5beta1" by people in this website by year, and whether "Integrin alpha5beta1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin alpha5beta1" by people in Profiles.
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Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin. PLoS One. 2016; 11(10):e0163732.
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A novel intracellular fibulin-1D variant binds to the cytoplasmic domain of integrin beta 1 subunit. Matrix Biol. 2015 Apr; 43:97-108.
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A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by a5?1 integrin in kidney mesangial cells. PLoS One. 2012; 7(3):e33350.
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Role of integrins in angiotensin II-induced proliferation of vascular smooth muscle cells. Am J Physiol Cell Physiol. 2011 Mar; 300(3):C647-56.
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Bradykinin B2 receptor interacts with integrin alpha5beta1 to transactivate epidermal growth factor receptor in kidney cells. Mol Pharmacol. 2010 Jul; 78(1):126-34.
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Integrin fibronectin receptors in matrix metalloproteinase-1-dependent invasion by breast cancer and mammary epithelial cells. Cancer Res. 2004 Dec 01; 64(23):8674-81.
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Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through alpha5beta1 integrin and PI 3-kinase. Invest Ophthalmol Vis Sci. 2003 Apr; 44(4):1704-15.