"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
|
| MeSH Number(s) |
D12.125.072.401.623.270
|
| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
|
Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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Liao X, Xiao J, Li SH, Xiao LL, Cheng B, Fu XB, Cui T, Liu HW. Critical role of the endogenous renin-angiotensin system in maintaining self-renewal and regeneration potential of epidermal stem cells. Biochim Biophys Acta Mol Basis Dis. 2019 10 01; 1865(10):2647-2656.
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Fuson AL, Komlosi P, Unlap TM, Bell PD, Peti-Peterdi J. Immunolocalization of a microsomal prostaglandin E synthase in rabbit kidney. Am J Physiol Renal Physiol. 2003 Sep; 285(3):F558-64.
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Litwin SE, Morgan JP. Effects of stimulation frequency on calcium transients in noninfarcted myocardium: modulation by chronic captopril treatment. J Card Fail. 1999 Sep; 5(3):224-35.
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Koide M, Carabello BA, Conrad CC, Buckley JM, DeFreyte G, Barnes M, Tomanek RJ, Wei CC, Dell'Italia LJ, Cooper G, Zile MR. Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation. Am J Physiol. 1999 Feb; 276(2 Pt 2):H350-8.
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Litwin SE, Katz SE, Morgan JP, Douglas PS. Long-term captopril treatment improves diastolic filling more than systolic performance in rats with large myocardial infarction. J Am Coll Cardiol. 1996 Sep; 28(3):773-81.
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Rumboldt Z, Simunic M, Bagatin J, Rumboldt M, Marinkovic M, Janezic A. Controlled multicentre comparison of captopril versus lisinopril in the treatment of mild-to-moderate arterial hypertension. Int J Clin Pharmacol Res. 1993; 13(1):35-41.
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Litwin SE, Morgan JP. Captopril enhances intracellular calcium handling and beta-adrenergic responsiveness of myocardium from rats with postinfarction failure. Circ Res. 1992 Oct; 71(4):797-807.
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Litwin SE, Raya TE, Warner A, Litwin CM, Goldman S. Effects of captopril on contractility after myocardial infarction: experimental observations. Am J Cardiol. 1991 Nov 18; 68(14):26D-34D.
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Fletcher SE, Fyfe DA, Case CL, Wiles HB, Upshur JK, Newman RB. Myocardial necrosis in a newborn after long-term maternal subcutaneous terbutaline infusion for suppression of preterm labor. Am J Obstet Gynecol. 1991 Nov; 165(5 Pt 1):1401-4.
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Ploth DW, Mackenzie HS. Tubuloglomerular feedback in one-kidney, one-clip hypertensive rats. Kidney Int Suppl. 1991 Jun; 32:S115-8.