"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
|
| MeSH Number(s) |
D12.125.072.401.623.270
|
| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
|
Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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Critical role of the endogenous renin-angiotensin system in maintaining self-renewal and regeneration potential of epidermal stem cells. Biochim Biophys Acta Mol Basis Dis. 2019 10 01; 1865(10):2647-2656.
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Immunolocalization of a microsomal prostaglandin E synthase in rabbit kidney. Am J Physiol Renal Physiol. 2003 Sep; 285(3):F558-64.
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Effects of stimulation frequency on calcium transients in noninfarcted myocardium: modulation by chronic captopril treatment. J Card Fail. 1999 Sep; 5(3):224-35.
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Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation. Am J Physiol. 1999 Feb; 276(2 Pt 2):H350-8.
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Distinct mechanisms of modulation of angiotensin II type I receptor gene expression in heart and aorta. Hypertension. 1997 May; 29(5):1104-8.
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Long-term captopril treatment improves diastolic filling more than systolic performance in rats with large myocardial infarction. J Am Coll Cardiol. 1996 Sep; 28(3):773-81.
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Controlled multicentre comparison of captopril versus lisinopril in the treatment of mild-to-moderate arterial hypertension. Int J Clin Pharmacol Res. 1993; 13(1):35-41.
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Captopril enhances intracellular calcium handling and beta-adrenergic responsiveness of myocardium from rats with postinfarction failure. Circ Res. 1992 Oct; 71(4):797-807.
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Effects of captopril on contractility after myocardial infarction: experimental observations. Am J Cardiol. 1991 Nov 18; 68(14):26D-34D.
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Myocardial necrosis in a newborn after long-term maternal subcutaneous terbutaline infusion for suppression of preterm labor. Am J Obstet Gynecol. 1991 Nov; 165(5 Pt 1):1401-4.