An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

Descriptor ID	D016178
MeSH Number(s)	D12.644.276.374.410.240.375 D12.776.395.240.300 D12.776.467.374.410.240.375 D23.529.374.410.240.375
Concept/Terms	Granulocyte-Macrophage Colony-Stimulating Factor Granulocyte-Macrophage Colony-Stimulating Factor Granulocyte Macrophage Colony Stimulating Factor CSF-2 Tumor-Cell Human GM Colony-Stimulating Factor Tumor Cell Human GM Colony Stimulating Factor GM-CSF Histamine-Producing Cell-Stimulating Factor Cell-Stimulating Factor, Histamine-Producing Histamine Producing Cell Stimulating Factor TC-GM-CSF Colony-Stimulating Factor, Granulocyte-Macrophage Colony Stimulating Factor, Granulocyte Macrophage CSF-GM

Below are MeSH descriptors whose meaning is more general than "Granulocyte-Macrophage Colony-Stimulating Factor".

Below are MeSH descriptors whose meaning is related to "Granulocyte-Macrophage Colony-Stimulating Factor".

Below are MeSH descriptors whose meaning is more specific than "Granulocyte-Macrophage Colony-Stimulating Factor".