Nerve Degeneration

"Nerve Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Descriptor ID	D009410
MeSH Number(s)	C23.550.737
Concept/Terms	Nerve Degeneration Nerve Degeneration Degeneration, Nerve Degenerations, Nerve Nerve Degenerations Neuron Degeneration Degeneration, Neuron Degenerations, Neuron Neuron Degenerations

Below are MeSH descriptors whose meaning is more general than "Nerve Degeneration".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Nerve Degeneration [C23.550.737]

Below are MeSH descriptors whose meaning is related to "Nerve Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Nerve Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nerve Degeneration" by people in this website by year, and whether "Nerve Degeneration" was a major or minor topic of these publications.

Bar chart showing 81 publications over 20 distinct years, with a maximum of 17 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	0	1
2000	0	2	2
2001	1	2	3
2002	1	0	1
2003	0	2	2
2004	3	2	5
2005	2	2	4
2006	3	4	7
2007	2	2	4
2008	11	6	17
2009	2	3	5
2010	1	5	6
2011	4	2	6
2012	0	1	1
2013	1	1	2
2014	3	1	4
2015	3	1	4
2016	0	1	1
2018	2	3	5

Below are the most recent publications written about "Nerve Degeneration" by people in Profiles.

Bosco A, Anderson SR, Breen KT, Romero CO, Steele MR, Chiodo VA, Boye SL, Hauswirth WW, Tomlinson S, Vetter ML. Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma. Mol Ther. 2018 10 03; 26(10):2379-2396.

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Ward R, Valenzuela JP, Li W, Dong G, Fagan SC, Ergul A. Poststroke cognitive impairment and hippocampal neurovascular remodeling: the impact of diabetes and sex. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1402-H1413.

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Alawieh A, Langley EF, Tomlinson S. Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice. Sci Transl Med. 2018 05 16; 10(441).

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Lee B, Baek JI, Min H, Bae SH, Moon K, Kim MA, Kim YR, Fogelgren B, Lipschutz JH, Lee KY, Bok J, Kim UK. Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing. Mol Neurobiol. 2018 Aug; 55(8):6518-6532.

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Killoy KM, Harlan BA, Pehar M, Helke KL, Johnson JA, Vargas MR. Decreased glutathione levels cause overt motor neuron degeneration in hSOD1WT over-expressing mice. Exp Neurol. 2018 04; 302:129-135.

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Farrand AQ, Gregory RA, Bäckman CM, Helke KL, Boger HA. Altered glutamate release in the dorsal striatum of the MitoPark mouse model of Parkinson's disease. Brain Res. 2016 11 15; 1651:88-94.

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Samantaray S, Knaryan VH, Shields DC, Cox AA, Haque A, Banik NL. Inhibition of Calpain Activation Protects MPTP-Induced Nigral and Spinal Cord Neurodegeneration, Reduces Inflammation, and Improves Gait Dynamics in Mice. Mol Neurobiol. 2015 Oct; 52(2):1054-66.

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Samantaray S, Knaryan VH, Patel KS, Mulholland PJ, Becker HC, Banik NL. Chronic intermittent ethanol induced axon and myelin degeneration is attenuated by calpain inhibition. Brain Res. 2015 Oct 05; 1622:7-21.

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Kruyer A, Soplop N, Strickland S, Norris EH. Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's Disease. Hypertension. 2015 Jul; 66(1):175-82.

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Akil O, Sun Y, Vijayakumar S, Zhang W, Ku T, Lee CK, Jones S, Grabowski GA, Lustig LR. Spiral ganglion degeneration and hearing loss as a consequence of satellite cell death in saposin B-deficient mice. J Neurosci. 2015 Feb 18; 35(7):3263-75.

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