Benzodioxoles

"Benzodioxoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds based on benzene fused to oxole. They can be formed from methylated CATECHOLS such as EUGENOL.

Descriptor ID	D052117
MeSH Number(s)	D03.383.246.118 D03.633.100.115
Concept/Terms	Benzodioxoles Benzodioxoles 1,3-Dioxindans 1,3 Dioxindans Methylenedioxybenzenes 1,3-Dioxaindans 1,3 Dioxaindans

Below are MeSH descriptors whose meaning is more general than "Benzodioxoles".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Dioxoles [D03.383.246]
Benzodioxoles [D03.383.246.118]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzodioxoles [D03.633.100.115]

Below are MeSH descriptors whose meaning is related to "Benzodioxoles".

Below are MeSH descriptors whose meaning is more specific than "Benzodioxoles".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Benzodioxoles" by people in this website by year, and whether "Benzodioxoles" was a major or minor topic of these publications.

Bar chart showing 14 publications over 8 distinct years, with a maximum of 4 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2015	1	0	1
2016	0	1	1
2017	1	0	1
2018	1	1	2
2019	1	2	3
2020	0	1	1
2021	1	3	4
2022	0	1	1

Below are the most recent publications written about "Benzodioxoles" by people in Profiles.

Szentpetery S, Foil K, Hendrix S, Gray S, Mingora C, Head B, Johnson D, Flume PA. A case report of CFTR modulator administration via carrier mother to treat meconium ileus in a F508del homozygous fetus. J Cyst Fibros. 2022 07; 21(4):721-724.

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Flume PA, Biner RF, Downey DG, Brown C, Jain M, Fischer R, De Boeck K, Sawicki GS, Chang P, Paz-Diaz H, Rubin JL, Yang Y, Hu X, Pasta DJ, Millar SJ, Campbell D, Wang X, Ahluwalia N, Owen CA, Wainwright CE. Long-term safety and efficacy of tezacaftor-ivacaftor in individuals with cystic fibrosis aged 12 years or older who are homozygous or heterozygous for Phe508del CFTR (EXTEND): an open-label extension study. Lancet Respir Med. 2021 07; 9(7):733-746.

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Khan M, Qiao F, Islam SMT, Dhammu TS, Kumar P, Won J, Singh AK, Singh I. GSNOR and ALDH2 alleviate traumatic spinal cord injury. Brain Res. 2021 05 01; 1758:147335.

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Islam SMT, Won J, Kim J, Qiao F, Singh AK, Khan M, Singh I. Detoxification of Reactive Aldehydes by Alda-1 Treatment Ameliorates Experimental Autoimmune Encephalomyelitis in Mice. Neuroscience. 2021 03 15; 458:31-42.

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O'Connor KE, Goodwin DL, NeSmith A, Garcia B, Mingora C, Ladores SL, Rowe SM, Krick S, Solomon GM. Elexacafator/tezacaftor/ivacaftor resolves subfertility in females with CF: A two center case series. J Cyst Fibros. 2021 05; 20(3):399-401.

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Wimborne HJ, Hu J, Takemoto K, Nguyen NT, Jaeschke H, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization. Toxicol Appl Pharmacol. 2020 06 01; 396:114982.

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Wimborne HJ, Takemoto K, Woster PM, Rockey DC, Lemasters JJ, Zhong Z. Aldehyde dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice. Free Radic Biol Med. 2019 12; 145:136-145.

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Walker S, Flume P, McNamara J, Solomon M, Chilvers M, Chmiel J, Harris RS, Haseltine E, Stiles D, Li C, Ahluwalia N, Zhou H, Owen CA, Sawicki G. A phase 3 study of tezacaftor in combination with ivacaftor in children aged 6 through 11?years with cystic fibrosis. J Cyst Fibros. 2019 09; 18(5):708-713.

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Flume PA. The study of CFTR modulators in the very young. Lancet Respir Med. 2019 04; 7(4):287-289.

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Flume PA, Suthoff ED, Kosinski M, Marigowda G, Quittner AL. Measuring recovery in health-related quality of life during and after pulmonary exacerbations in patients with cystic fibrosis. J Cyst Fibros. 2019 09; 18(5):737-742.

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