"Isoquinolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
| Descriptor ID |
D007546
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| MeSH Number(s) |
D03.633.100.531
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Isoquinolines".
Below are MeSH descriptors whose meaning is more specific than "Isoquinolines".
This graph shows the total number of publications written about "Isoquinolines" by people in this website by year, and whether "Isoquinolines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 2 | 3 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isoquinolines" by people in Profiles.
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Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells. Eur J Immunol. 2020 09; 50(9):1386-1399.
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Effect of the CRAC Peptide, VLNYYVW, on mPTP Opening in Rat Brain and Liver Mitochondria. Int J Mol Sci. 2016 Dec 13; 17(12).
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Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs). J Med Chem. 2016 05 26; 59(10):4778-89.
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BK channel regulation by phosphodiesterase type 1: a novel signaling pathway controlling human detrusor smooth muscle function. Am J Physiol Renal Physiol. 2016 05 15; 310(10):F994-9.
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Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria. Arch Biochem Biophys. 2015 Dec 01; 587:70-7.
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Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1. Retrovirology. 2015 Jul 16; 12:63.
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Design and synthesis of a tetrahydroisoquinoline-based hydroxamate derivative (ZYJ-34v), an oral active histone deacetylase inhibitor with potent antitumor activity. Chem Biol Drug Des. 2013 Aug; 82(2):125-30.
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Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. Am J Physiol Renal Physiol. 2012 Apr 01; 302(7):F801-8.
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Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. PLoS One. 2011; 6(10):e25539.
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Lucifer Yellow as a live cell fluorescent probe for imaging water transport in subcellular organelles. Appl Spectrosc. 2011 Jan; 65(1):20-5.