"Receptor, Bradykinin B2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A constitutively expressed subtype of bradykinin receptor that may play a role in the acute phase of the inflammatory and pain response. It has high specificity for intact forms of BRADYKININ and KALLIDIN. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.
| Descriptor ID |
D043782
|
| MeSH Number(s) |
D12.776.543.750.695.080.500 D12.776.543.750.720.600.220.500 D12.776.543.750.750.555.220.500
|
| Concept/Terms |
Receptor, Bradykinin B2- Receptor, Bradykinin B2
- B2 Receptor, Bradykinin
- Receptor, Bradykinin Type 2
- Bradykinin Type 2 Receptor
- Bradykinin B2 Receptors
- B2 Receptors, Bradykinin
- Receptors, Bradykinin B2
- Bradykinin B2 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Bradykinin B2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Bradykinin [D12.776.543.750.695.080]
- Receptor, Bradykinin B2 [D12.776.543.750.695.080.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Bradykinin [D12.776.543.750.720.600.220]
- Receptor, Bradykinin B2 [D12.776.543.750.720.600.220.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Bradykinin [D12.776.543.750.750.555.220]
- Receptor, Bradykinin B2 [D12.776.543.750.750.555.220.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Bradykinin B2".
This graph shows the total number of publications written about "Receptor, Bradykinin B2" by people in this website by year, and whether "Receptor, Bradykinin B2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 5 | 1 | 6 |
| 2007 | 2 | 1 | 3 |
| 2008 | 3 | 0 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 3 | 4 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Bradykinin B2" by people in Profiles.
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Heteromerization fingerprints between bradykinin B2 and thromboxane TP receptors in native cells. PLoS One. 2019; 14(5):e0216908.
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Mechanisms of bradykinin-induced expression of connective tissue growth factor and nephrin in podocytes. Am J Physiol Renal Physiol. 2015 Dec 01; 309(11):F980-90.
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Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment. PLoS One. 2015; 10(6):e0128601.
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FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys. Drug Dev Res. 2014 Jun; 75(4):211-23.
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Protein expression, biochemical pharmacology of signal transduction, and relation to intraocular pressure modulation by bradykinin B2 receptors in ciliary muscle. Mol Vis. 2013; 19:1356-70.
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The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers. J Biol Chem. 2013 Jun 28; 288(26):18872-84.
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Global renal gene expression profiling analysis in B2-kinin receptor null mice: impact of diabetes. PLoS One. 2012; 7(9):e44714.
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Bradykinin activation of extracellular signal-regulated kinases in human trabecular meshwork cells. Exp Eye Res. 2011 Jun; 92(6):495-501.
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Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. J Pharmacol Exp Ther. 2010 Sep 01; 334(3):775-83.
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Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice. Endocrinology. 2010 Aug; 151(8):3536-42.