Receptors, Dopamine D2

"Receptors, Dopamine D2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D2-class receptor genes contain INTRONS, and the receptors inhibit ADENYLYL CYCLASES.

Descriptor ID	D017448
MeSH Number(s)	D12.776.543.750.670.300.400.500 D12.776.543.750.695.150.400.500 D12.776.543.750.720.330.400.500
Concept/Terms	Receptors, Dopamine D2 Receptors, Dopamine D2 Dopamine-D2 Receptor Dopamine D2 Receptor Receptor, Dopamine-D2 Dopamine D2 Receptors D2 Receptors, Dopamine

Below are MeSH descriptors whose meaning is more general than "Receptors, Dopamine D2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Biogenic Amine [D12.776.543.750.670]
Receptors, Catecholamine [D12.776.543.750.670.300]
Receptors, Dopamine [D12.776.543.750.670.300.400]
Receptors, Dopamine D2 [D12.776.543.750.670.300.400.500]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Receptors, Catecholamine [D12.776.543.750.695.150]
Receptors, Dopamine [D12.776.543.750.695.150.400]
Receptors, Dopamine D2 [D12.776.543.750.695.150.400.500]
Receptors, Neurotransmitter [D12.776.543.750.720]
Receptors, Catecholamine [D12.776.543.750.720.330]
Receptors, Dopamine [D12.776.543.750.720.330.400]
Receptors, Dopamine D2 [D12.776.543.750.720.330.400.500]

Below are MeSH descriptors whose meaning is related to "Receptors, Dopamine D2".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Dopamine D2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Dopamine D2" by people in this website by year, and whether "Receptors, Dopamine D2" was a major or minor topic of these publications.

Bar chart showing 61 publications over 27 distinct years, with a maximum of 7 publications in 1993

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	5	2	7
1994	2	2	4
1995	3	0	3
1996	2	1	3
1997	2	0	2
1998	2	2	4
1999	1	0	1
2000	1	0	1
2001	2	0	2
2002	1	1	2
2003	1	0	1
2004	2	0	2
2005	0	1	1
2006	2	1	3
2007	1	0	1
2008	0	1	1
2010	3	2	5
2012	1	1	2
2013	1	0	1
2014	1	1	2
2015	1	1	2
2016	0	1	1
2017	2	1	3
2018	1	2	3
2019	1	0	1
2020	0	1	1
2021	1	1	2

Below are the most recent publications written about "Receptors, Dopamine D2" by people in Profiles.

Brown RW, Varnum CG, Wills LJ, Peeters LD, Gass JT. Modulation of mGlu5 improves sensorimotor gating deficits in rats neonatally treated with quinpirole through changes in dopamine D2 signaling. Pharmacol Biochem Behav. 2021 12; 211:173292.

View in: PubMed
Kruyer A, Parrilla-Carrero J, Powell C, Brandt L, Gutwinski S, Angelis A, Chalhoub RM, Jhou TC, Kalivas PW, Amato D. Accumbens D2-MSN hyperactivity drives antipsychotic-induced behavioral supersensitivity. Mol Psychiatry. 2021 11; 26(11):6159-6169.

View in: PubMed
Uzuneser TC, Weiss EM, Dahlmanns J, Kalinichenko LS, Amato D, Kornhuber J, Alzheimer C, Hellmann J, Kaindl J, Hübner H, Löber S, Gmeiner P, Grömer TW, Müller CP. Presynaptic vesicular accumulation is required for antipsychotic efficacy in psychotic-like rats. J Psychopharmacol. 2021 01; 35(1):65-77.

View in: PubMed
DeCarlo AN, Jennings K, Pratt SL, Burnett CR, Long NM, Bridges WC, Kojima C. Bovine dopamine type-2 receptor SNP has no effect on growth, semen characteristics and prolactin concentrations in beef bulls treated with a dopamine agonist. Anim Reprod Sci. 2019 Aug; 207:73-82.

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Larson TA, Winkler MC, Stafford J, Levis SC, O'Neill CE, Bachtell RK. Role of dopamine D2-like receptors and their modulation by adenosine receptor stimulation in the reinstatement of methamphetamine seeking. Psychopharmacology (Berl). 2019 Apr; 236(4):1207-1218.

View in: PubMed
Amato D, Canneva F, Cumming P, Maschauer S, Groos D, Dahlmanns JK, Grömer TW, Chiofalo L, Dahlmanns M, Zheng F, Kornhuber J, Prante O, Alzheimer C, von Hörsten S, Müller CP. A dopaminergic mechanism of antipsychotic drug efficacy, failure, and failure reversal: the role of the dopamine transporter. Mol Psychiatry. 2020 09; 25(9):2101-2118.

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Roberts-Wolfe D, Bobadilla AC, Heinsbroek JA, Neuhofer D, Kalivas PW. Drug Refraining and Seeking Potentiate Synapses on Distinct Populations of Accumbens Medium Spiny Neurons. J Neurosci. 2018 08 08; 38(32):7100-7107.

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Schacht JP, Voronin KE, Randall PK, Anton RF. Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial. Neuropsychopharmacology. 2018 05; 43(6):1247-1256.

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Amato D, Vernon AC, Papaleo F. Dopamine, the antipsychotic molecule: A perspective on mechanisms underlying antipsychotic response variability. Neurosci Biobehav Rev. 2018 02; 85:146-159.

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Heinsbroek JA, Neuhofer DN, Griffin WC, Siegel GS, Bobadilla AC, Kupchik YM, Kalivas PW. Loss of Plasticity in the D2-Accumbens Pallidal Pathway Promotes Cocaine Seeking. J Neurosci. 2017 01 25; 37(4):757-767.

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