"Receptors, Prostaglandin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that bind prostaglandins with high affinity and trigger intracellular changes which influence the behavior of cells. Prostaglandin receptor subtypes have been tentatively named according to their relative affinities for the endogenous prostaglandins. They include those which prefer prostaglandin D2 (DP receptors), prostaglandin E2 (EP1, EP2, and EP3 receptors), prostaglandin F2-alpha (FP receptors), and prostacyclin (IP receptors).
| Descriptor ID |
D011982
|
| MeSH Number(s) |
D12.776.543.750.695.200.700
|
| Concept/Terms |
Receptors, Prostaglandin- Receptors, Prostaglandin
- Receptor, Prostaglandin
- Prostaglandin Receptors
- Prostaglandin Receptor
- Receptors, Prostaglandins
- Prostaglandins Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin".
This graph shows the total number of publications written about "Receptors, Prostaglandin" by people in this website by year, and whether "Receptors, Prostaglandin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 3 | 0 | 3 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Prostaglandin" by people in Profiles.
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CRTH2 antagonist MK-7246: a synthetic evolution from discovery through development. J Org Chem. 2012 Mar 02; 77(5):2299-309.
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Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms. Int Immunol. 2009 Jan; 21(1):1-17.
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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. Int Immunol. 2009 Jan; 21(1):81-93.
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CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L767-79.
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Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins. Dev Biol. 2006 Jan 15; 289(2):263-72.
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Differential modulation of prostaglandin receptor mRNA abundance by prostaglandins in primary cultured rat hepatocytes. Mol Cell Biochem. 2004 Nov; 266(1-2):183-9.
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Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts. Mol Endocrinol. 2003 Aug; 17(8):1607-21.
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Cyclooxygenase-2 and colorectal cancer. Prog Exp Tumor Res. 2003; 37:124-37.
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Increased prostacyclin and PGE2 stimulated cAMP production by macrophages from endotoxin-tolerant rats. Am J Physiol. 1998 05; 274(5):C1238-44.
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Preoperative thromboxane A2/prostaglandin H2 receptor activity predicts early graft thrombosis. J Vasc Surg. 1998 Feb; 27(2):317-25; discussion 326-8.