"Thromboxane A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS).
| Descriptor ID |
D013928
|
| MeSH Number(s) |
D10.251.355.255.100.825.800 D10.251.355.310.166.971.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thromboxane A2".
Below are MeSH descriptors whose meaning is more specific than "Thromboxane A2".
This graph shows the total number of publications written about "Thromboxane A2" by people in this website by year, and whether "Thromboxane A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 2 | 3 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thromboxane A2" by people in Profiles.
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Selective cyclooxygenase-2 inhibitor suppresses renal thromboxane production but not proliferative lesions in the MRL/lpr murine model of lupus nephritis. Am J Med Sci. 2011 Feb; 341(2):101-5.
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A thromboxane A(2) system in the Atlantic stingray, Dasyatis sabina. Gen Comp Endocrinol. 2003 Feb 01; 130(2):157-64.
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Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2? Circulation. 2002 Apr 09; 105(14):1620-2.
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Thromboxane A(2) receptors: where have you gone? Prostaglandins Other Lipid Mediat. 2000 Mar; 60(4-6):175-89.
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Cloning and characterization of an endogenous COS-7 cell thromboxane A2 receptor. Biochim Biophys Acta. 1998 May 27; 1403(1):109-14.
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Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthase activity. Shock. 1998 May; 9(5):359-63.
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Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):4888-93.
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Stimulation of rat mesangial cell thromboxane A2 receptors inhibits particulate but not soluble guanylyl cyclase. Am J Physiol. 1996 Jan; 270(1 Pt 2):F31-8.
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Thromboxane A2 receptors. J Lipid Mediat Cell Signal. 1995 Oct; 12(2-3):361-78.
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Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets. J Pharmacol Exp Ther. 1994 Sep; 270(3):1192-6.