Aryl Hydrocarbon Hydroxylases
"Aryl Hydrocarbon Hydroxylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
| Descriptor ID |
D001189
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| MeSH Number(s) |
D08.244.453.005 D08.811.682.690.708.170.010 D12.776.422.220.453.010
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aryl Hydrocarbon Hydroxylases".
Below are MeSH descriptors whose meaning is more specific than "Aryl Hydrocarbon Hydroxylases".
This graph shows the total number of publications written about "Aryl Hydrocarbon Hydroxylases" by people in this website by year, and whether "Aryl Hydrocarbon Hydroxylases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
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Below are the most recent publications written about "Aryl Hydrocarbon Hydroxylases" by people in Profiles.
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Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. Int J Cancer. 2012 Apr 15; 130(8):1898-907.
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Evaluation of a CYP2C19 genotype panel on the GenMark eSensor? platform and the comparison to the Autogenomics Infiniti? and Luminex CYP2C19 panels. Clin Chim Acta. 2011 May 12; 412(11-12):1133-7.
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Characterization of 107 genomic DNA reference materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1: a GeT-RM and Association for Molecular Pathology collaborative project. J Mol Diagn. 2010 Nov; 12(6):835-46.
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Differential induction of CYP1A1 and CYP1B1 by benzo[a]pyrene in oral squamous cell carcinoma cell lines and by tobacco smoking in oral mucosa. Oral Oncol. 2009 Nov; 45(11):980-5.
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Comparison of performance of three commercial platforms for warfarin sensitivity genotyping. Clin Chim Acta. 2009 Aug; 406(1-2):143-7.
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Interethnic differences of CYP2C9 alleles in healthy Hungarian and Roma population samples: relationship to worldwide allelic frequencies. Blood Cells Mol Dis. 2009 Nov-Dec; 43(3):239-42.
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Detection and identification of cytochrome P-450 2C9 alleles *1, *2, and *3 by high-resolution melting curve analysis of PCR amplicons. Am J Clin Pathol. 2006 Apr; 125(4):584-91.
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Characterization of recombinant CYP2C11: a vitamin D 25-hydroxylase and 24-hydroxylase. Am J Physiol Endocrinol Metab. 2005 Apr; 288(4):E753-60.
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Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice. Drug Metab Dispos. 1996 Dec; 24(12):1287-90.