"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 3 | 3 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 1 | 2 | 3 |
| 2003 | 2 | 3 | 5 |
| 2004 | 4 | 0 | 4 |
| 2005 | 0 | 3 | 3 |
| 2006 | 6 | 1 | 7 |
| 2007 | 2 | 3 | 5 |
| 2008 | 8 | 3 | 11 |
| 2009 | 1 | 4 | 5 |
| 2010 | 4 | 4 | 8 |
| 2011 | 4 | 1 | 5 |
| 2012 | 4 | 1 | 5 |
| 2013 | 8 | 2 | 10 |
| 2014 | 9 | 2 | 11 |
| 2015 | 1 | 5 | 6 |
| 2016 | 4 | 3 | 7 |
| 2017 | 6 | 3 | 9 |
| 2018 | 2 | 3 | 5 |
| 2019 | 5 | 2 | 7 |
| 2020 | 3 | 2 | 5 |
| 2021 | 4 | 3 | 7 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Synapses" by people in Profiles.
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NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia-like behavior and reductions in excitatory synapses. Elife. 2023 02 13; 12.
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Astrocyte Heterogeneity in Regulation of Synaptic Activity. Cells. 2022 10 05; 11(19).
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Astrocyte regulation of synaptic signaling in psychiatric disorders. Neuropsychopharmacology. 2023 01; 48(1):21-36.
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Synaptic Plasticity 101: The Story of the AMPA Receptor for the Brain Stimulation Practitioner. Neuromodulation. 2022 Dec; 25(8):1289-1298.
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Extrasynaptic therapeutic targets in substance use and stress disorders. Trends Pharmacol Sci. 2022 01; 43(1):56-68.
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The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior in mice. Nat Commun. 2021 08 23; 12(1):5080.
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Alternative splicing of GluN1 gates glycine site-dependent nonionotropic signaling by NMDAR receptors. Proc Natl Acad Sci U S A. 2021 07 06; 118(27).
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Quiet on the Set! Astroglia Star in Silent Synaptogenesis and Cocaine Memory Formation. Biol Psychiatry. 2021 02 15; 89(4):328-330.
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Complement Drives Synaptic Degeneration and Progressive Cognitive Decline in the Chronic Phase after Traumatic Brain Injury. J Neurosci. 2021 02 24; 41(8):1830-1843.
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Astrocytes in Addictive Disorders. Adv Neurobiol. 2021; 26:231-254.