"Osteitis Deformans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry.
| Descriptor ID |
D010001
|
| MeSH Number(s) |
C05.116.692
|
| Concept/Terms |
Osteitis Deformans- Osteitis Deformans
- Paget's Disease of Bone
- Pagets Disease, Bone
- Paget Disease, Bone
- Osseous Paget's Disease
- Paget Disease of Bone
|
Below are MeSH descriptors whose meaning is more general than "Osteitis Deformans".
Below are MeSH descriptors whose meaning is more specific than "Osteitis Deformans".
This graph shows the total number of publications written about "Osteitis Deformans" by people in this website by year, and whether "Osteitis Deformans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 4 | 0 | 4 |
| 2005 | 1 | 0 | 1 |
| 2006 | 3 | 1 | 4 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Osteitis Deformans" by people in Profiles.
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Tartrate-resistant acid phosphatase 5b, but not periostin, is useful for assessing Paget's disease of bone. Bone. 2019 07; 124:132-136.
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NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone. Bone. 2017 Aug; 101:236-244.
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SOCS-1/3 participation in FGF-2 signaling to modulate RANK ligand expression in paget's disease of bone. J Cell Biochem. 2013 Sep; 114(9):2032-8.
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CXCL5 stimulation of RANK ligand expression in Paget's disease of bone. Lab Invest. 2013 Apr; 93(4):472-9.
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Mutant p62P392L stimulation of osteoclast differentiation in Paget's disease of bone. Endocrinology. 2011 Nov; 152(11):4180-9.
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FGF-2 stimulation of RANK ligand expression in Paget's disease of bone. Mol Endocrinol. 2009 Sep; 23(9):1445-54.
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Osteoclast inhibitory peptide-1 (OIP-1) inhibits measles virus nucleocapsid protein stimulated osteoclast formation/activity. J Cell Biochem. 2008 Jul 01; 104(4):1500-8.
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Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. J Clin Invest. 2007 Jan; 117(1):133-42.
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Experimental models of Paget's disease. J Bone Miner Res. 2006 Dec; 21 Suppl 2:P55-7.
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Elevated serum kininogen in patients with Paget's disease of bone: a role in marrow stromal/preosteoblast cell proliferation. J Cell Biochem. 2006 Aug 15; 98(6):1681-8.