Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
Descriptor ID |
D048868
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MeSH Number(s) |
D12.644.360.024 D12.776.157.057 D12.776.476.024
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
1996 | 4 | 1 | 5 |
1997 | 2 | 0 | 2 |
1998 | 5 | 0 | 5 |
1999 | 2 | 0 | 2 |
2000 | 4 | 1 | 5 |
2001 | 1 | 1 | 2 |
2002 | 2 | 2 | 4 |
2003 | 3 | 5 | 8 |
2004 | 2 | 4 | 6 |
2005 | 2 | 6 | 8 |
2006 | 2 | 5 | 7 |
2007 | 3 | 4 | 7 |
2008 | 3 | 1 | 4 |
2009 | 2 | 3 | 5 |
2010 | 8 | 9 | 17 |
2011 | 4 | 3 | 7 |
2012 | 2 | 6 | 8 |
2013 | 6 | 6 | 12 |
2014 | 4 | 1 | 5 |
2015 | 3 | 11 | 14 |
2016 | 4 | 2 | 6 |
2017 | 3 | 3 | 6 |
2018 | 3 | 2 | 5 |
2019 | 4 | 3 | 7 |
2020 | 4 | 3 | 7 |
2021 | 2 | 2 | 4 |
2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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Delta-like ligand-4 regulates Notch-mediated maturation of second heart field progenitor-derived pharyngeal arterial endothelial cells. J Cell Mol Med. 2022 10; 26(20):5181-5194.
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DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway. Sci Signal. 2022 01 04; 15(715):eabh2290.
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GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis. EMBO J. 2021 10 18; 40(20):e107766.
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Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome. Circ Res. 2021 09 17; 129(7):735-750.
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DZIP1 regulates mammalian cardiac valve development through a Cby1-?-catenin mechanism. Dev Dyn. 2021 10; 250(10):1432-1449.
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PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis. JCI Insight. 2021 03 08; 6(5).
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The role of disabled-2 (Dab2) in diseases. Gene. 2021 Feb 15; 769:145202.
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Differential regulation of a placental SAM68 and sFLT1 gene pathway and the relevance to maternal vitamin D sufficiency. Pregnancy Hypertens. 2020 Oct; 22:196-203.
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Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression. Development. 2020 09 11; 147(17).
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Long noncoding RNA H19X is a key mediator of TGF-?-driven fibrosis. J Clin Invest. 2020 09 01; 130(9):4888-4905.