"Quinolinic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
| Descriptor ID |
D017378
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| MeSH Number(s) |
D03.383.725.822.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Quinolinic Acid".
Below are MeSH descriptors whose meaning is more specific than "Quinolinic Acid".
This graph shows the total number of publications written about "Quinolinic Acid" by people in this website by year, and whether "Quinolinic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Quinolinic Acid" by people in Profiles.
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Quinolinate as a Marker for Kynurenine Metabolite Formation and the Unresolved Question of NAD+ Synthesis During Inflammation and Infection. Front Immunol. 2020; 11:31.
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A murine model of the eosinophilia-myalgia syndrome induced by 1,1'-ethylidenebis (L-tryptophan). J Clin Invest. 1994 Apr; 93(4):1473-80.
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Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome. Arthritis Rheum. 1992 Sep; 35(9):1097-105.
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Autoradiographic localization of gamma-aminobutyric acidA receptors within the ventral tegmental area. Neurochem Res. 1992 Jan; 17(1):101-6.
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Alterations in tryptophan metabolism in the toxic oil syndrome and in the eosinophilia-myalgia syndrome. J Rheumatol. 1992 Jan; 19(1):69-73.
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GABAA receptors containing alpha 1 and beta 2 subunits are mainly localized on neurons in the ventral pallidum. Synapse. 1991 Jun; 8(2):75-85.
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gamma-Aminobutyric acid and mu-opioid receptor localization and adaptation in the basal forebrain. Adv Exp Med Biol. 1991; 295:101-17.
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AIDS dementia may be linked to metabolite of tryptophan. JAMA. 1990 Jul 18; 264(3):305-6.
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Changes in gamma-aminobutyric acid, mu-opioid and neurotensin receptors in the accumbens-pallidal projection after discrete quinolinic acid lesions in the nucleus accumbens. Brain Res. 1990 Mar 12; 511(1):41-54.