"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
| Descriptor ID |
D016232
|
| MeSH Number(s) |
D12.644.276.400 D12.776.467.400 D23.529.400
|
| Concept/Terms |
Endothelins- Endothelins
- Endothelium-Derived Vasoconstrictor Factors
- Vasoconstrictor Factors, Endothelium-Derived
- Endothelin
|
Below are MeSH descriptors whose meaning is more general than "Endothelins".
Below are MeSH descriptors whose meaning is more specific than "Endothelins".
This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 |
| 1996 | 4 | 0 | 4 |
| 1997 | 1 | 2 | 3 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Endothelins" by people in Profiles.
-
Porphyromonas gingivalis infection upregulates the endothelin (ET) system in brain microvascular endothelial cells. Can J Physiol Pharmacol. 2022 Jul 01; 100(7):679-688.
-
Brain Vasculature and Cognition. Arterioscler Thromb Vasc Biol. 2019 04; 39(4):593-602.
-
Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin. Elife. 2019 02 08; 8.
-
Endothelin and diabetic complications: a brain-centric view. Physiol Res. 2018 06 27; 67(Suppl 1):S83-S94.
-
The Fourteenth International Conference on Endothelin (ET-14), Savannah, U.S.A. Life Sci. 2016 Aug 15; 159:2-9.
-
Variations on a theme: ET-14 notes from mentor and trainees. Life Sci. 2016 Aug 15; 159:12-14.
-
25 years of endothelin research: the next generation. Life Sci. 2014 Nov 24; 118(2):77-86.
-
Endothelin--biology and disease. Cell Signal. 2010 Nov; 22(11):1615-25.
-
Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease. Am J Physiol Gastrointest Liver Physiol. 2009 Jul; 297(1):G27-33.
-
Interleukin-10 attenuates vascular responses to endothelin-1 via effects on ERK1/2-dependent pathway. Am J Physiol Heart Circ Physiol. 2009 Feb; 296(2):H489-96.