Mixed Connective Tissue Disease
"Mixed Connective Tissue Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
| Descriptor ID |
D008947
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| MeSH Number(s) |
C17.300.540
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mixed Connective Tissue Disease".
Below are MeSH descriptors whose meaning is more specific than "Mixed Connective Tissue Disease".
This graph shows the total number of publications written about "Mixed Connective Tissue Disease" by people in this website by year, and whether "Mixed Connective Tissue Disease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
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Below are the most recent publications written about "Mixed Connective Tissue Disease" by people in Profiles.
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Autoantibody testing for autoimmune disease. Clin Chest Med. 2010 Sep; 31(3):415-22.
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Pulmonary manifestations of scleroderma and mixed connective tissue disease. Clin Chest Med. 2010 Sep; 31(3):433-49.
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Sarcoidosis in patients with mixed connective tissue disease: clinical, genetic, serological and histological observations. Rheumatol Int. 2008 Jun; 28(8):743-7.
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Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin-1, in patients with scleroderma and other connective tissue diseases. J Immunol. 1999 Jul 15; 163(2):1066-72.
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Long term follow-up of children with mixed connective tissue disease. Lupus. 1996 Jun; 5(3):221-6.
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Association of immunoglobulin Km and Gm allotypes with specific antinuclear antibodies and disease susceptibility among connective tissue disease patients. Arthritis Rheum. 1991 Apr; 34(4):453-8.
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Spontaneous formation of an anti-S alloantibody in association with mixed connective tissue disease. Ann Clin Lab Sci. 1987 Jan-Feb; 17(1):60-2.