"Marfan Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
| Descriptor ID |
D008382
|
| MeSH Number(s) |
C05.116.099.674 C14.240.400.725 C14.280.400.725 C16.131.077.550 C16.131.240.400.720 C16.320.540 C17.300.500
|
| Concept/Terms |
Marfan Syndrome- Marfan Syndrome
- Syndrome, Marfan
- Marfan Syndrome, Type I
- Marfan's Syndrome
- Marfans Syndrome
- Syndrome, Marfan's
|
Below are MeSH descriptors whose meaning is more general than "Marfan Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Marfan Syndrome".
This graph shows the total number of publications written about "Marfan Syndrome" by people in this website by year, and whether "Marfan Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 3 | 1 | 4 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 1 | 4 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 3 | 0 | 3 |
| 2020 | 3 | 0 | 3 |
| 2021 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Marfan Syndrome" by people in Profiles.
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Molecular characterization and investigation of the role of genetic variation in phenotypic variability and response to treatment in a large pediatric Marfan syndrome cohort. Genet Med. 2022 05; 24(5):1045-1053.
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Mitral Valve Prolapse and Its Motley Crew-Syndromic Prevalence, Pathophysiology, and Progression of a Common Heart Condition. J Am Heart Assoc. 2021 07 06; 10(13):e020919.
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Pathophysiology and Pathogenesis of Marfan Syndrome. Adv Exp Med Biol. 2021; 1348:185-206.
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Connective Tissue Disorders and Cardiovascular Complications: The Indomitable Role of Transforming Growth Factor-? Signaling. Adv Exp Med Biol. 2021; 1348:161-184.
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Recruitment, retention, and adherence in a clinical trial: The Pediatric Heart Network's Marfan Trial experience. Clin Trials. 2020 12; 17(6):684-695.
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The pattern and progression of hearing loss in Marfan Syndrome: A study of children and young adults. Int J Pediatr Otorhinolaryngol. 2020 Nov; 138:110207.
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Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome. J Pediatr. 2020 07; 222:213-220.e5.
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Endovascular Trapping of Large Cervical Carotid Pseudoaneurysm in Marfan Syndrome Presenting with Progressive Respiratory Distress. World Neurosurg. 2019 Mar; 123:323-327.
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Health-Related Quality of Life in Children and Young Adults with Marfan Syndrome. J Pediatr. 2019 01; 204:250-255.e1.
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Influence of Aortic Stiffness on Aortic-Root Growth Rate and Outcome in Patients With the Marfan Syndrome. Am J Cardiol. 2018 05 01; 121(9):1094-1101.