cdc42 GTP-Binding Protein
"cdc42 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS. It is associated with a diverse array of cellular functions including cytoskeletal changes, filopodia formation and transport through the GOLGI APPARATUS. This enzyme was formerly listed as EC 3.6.1.47.
Descriptor ID |
D020764
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MeSH Number(s) |
D08.811.277.040.330.300.400.700.050 D12.644.360.525.700.050 D12.776.157.325.515.700.050 D12.776.476.525.700.050
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Concept/Terms |
cdc42 GTP-Binding Protein- cdc42 GTP-Binding Protein
- GTP-Binding Protein, cdc42
- cdc42 GTP Binding Protein
- p21 cdc42
- cdc42, p21
- cdc42 Protein
- G25K Protein
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Below are MeSH descriptors whose meaning is more general than "cdc42 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "cdc42 GTP-Binding Protein".
This graph shows the total number of publications written about "cdc42 GTP-Binding Protein" by people in this website by year, and whether "cdc42 GTP-Binding Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2013 | 1 | 1 | 2 |
2014 | 0 | 2 | 2 |
2015 | 2 | 0 | 2 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "cdc42 GTP-Binding Protein" by people in Profiles.
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Dynamin Binding Protein (Tuba) Deficiency Inhibits Ciliogenesis and Nephrogenesis in Vitro and in Vivo. J Biol Chem. 2016 Apr 15; 291(16):8632-43.
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Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015 May; 56(5):3361-70.
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Lipopolysaccharide induces inducible nitric oxide synthase-dependent podocyte dysfunction via a hypoxia-inducible factor 1a and cell division control protein 42 and Ras-related C3 botulinum toxin substrate 1 pathway. Free Radic Biol Med. 2015 Jul; 84:185-195.
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Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. Oncotarget. 2014 Nov 30; 5(22):11709-22.
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Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation. J Biol Chem. 2014 Sep 19; 289(38):26383-26394.
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Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol. 2013 Sep; 24(9):1435-50.
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SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility. J Clin Endocrinol Metab. 2013 May; 98(5):E973-80.
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The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells. J Biol Chem. 2011 Jun 24; 286(25):22469-77.
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Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. J Am Soc Nephrol. 2010 May; 21(5):833-43.
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Heterogeneity in retinoic acid signaling in neuroblastomas: Role of matrix metalloproteinases in retinoic acid-induced differentiation. Biochim Biophys Acta. 2007 Sep; 1772(9):1093-102.