"GABA Modulators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
| Descriptor ID |
D018757
|
| MeSH Number(s) |
D27.505.519.625.240.500 D27.505.696.577.240.500
|
| Concept/Terms |
GABA Modulators- GABA Modulators
- Modulators, GABA
- GABAergic Modulators
- Modulators, GABAergic
- gamma-Aminobutyric Acid Modulators
- Acid Modulators, gamma-Aminobutyric
- Modulators, gamma-Aminobutyric Acid
- gamma Aminobutyric Acid Modulators
|
Below are MeSH descriptors whose meaning is more general than "GABA Modulators".
Below are MeSH descriptors whose meaning is more specific than "GABA Modulators".
This graph shows the total number of publications written about "GABA Modulators" by people in this website by year, and whether "GABA Modulators" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "GABA Modulators" by people in Profiles.
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Pervasive refusal syndrome: A misnomer for catatonia. Asian J Psychiatr. 2015 Dec; 18:113.
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Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics. Psychopharmacology (Berl). 2013 Jun; 227(4):627-37.
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Multisite, double-blind, randomized, controlled study of pregabalin for essential tremor. Mov Disord. 2013 Feb; 28(2):249-50.
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Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms. J Clin Psychopharmacol. 2009 Aug; 29(4):334-42.
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Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA. 2007 Oct 10; 298(14):1641-51.
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Self-reported sleep, sleepiness, and repeated alcohol withdrawals: a randomized, double blind, controlled comparison of lorazepam vs gabapentin. J Clin Sleep Med. 2007 Feb 15; 3(1):24-32.
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Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). Am J Physiol Renal Physiol. 2006 Aug; 291(2):F314-21.
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Lorazepam and MK-801 effects on behavioral and electrographic indices of alcohol withdrawal sensitization. Brain Res. 2005 Dec 14; 1065(1-2):92-106.
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Full neurologic recovery after fulminant thrombotic thrombocytopenic purpura with status epilepticus. Seizure. 2004 Dec; 13(8):549-52.
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Emergency management of status epilepticus in children. J S C Med Assoc. 2004 Dec; 100(12):347-51.