Minichromosome Maintenance Complex Component 3
"Minichromosome Maintenance Complex Component 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.
| Descriptor ID |
D064126
|
| MeSH Number(s) |
D08.811.277.040.025.159.186.300 D08.811.399.340.186.300 D12.776.167.409.300 D12.776.660.235.500.300 D12.776.664.235.750.300
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| Concept/Terms |
Minichromosome Maintenance Complex Component 3- Minichromosome Maintenance Complex Component 3
- DNA Replication Licensing Factor MCM3
- RLF Subunit beta
- Subunit beta, RLF
- beta, RLF Subunit
- DNA Polymerase alpha Holoenzyme-associated Protein P1
- DNA Polymerase alpha Holoenzyme associated Protein P1
|
Below are MeSH descriptors whose meaning is more general than "Minichromosome Maintenance Complex Component 3".
Below are MeSH descriptors whose meaning is more specific than "Minichromosome Maintenance Complex Component 3".
This graph shows the total number of publications written about "Minichromosome Maintenance Complex Component 3" by people in this website by year, and whether "Minichromosome Maintenance Complex Component 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "Minichromosome Maintenance Complex Component 3" by people in Profiles.
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Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):8079-84.
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E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 1998 Jul 15; 12(14):2120-30.