"Pepsin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
| Descriptor ID |
D010434
|
| MeSH Number(s) |
D08.811.277.656.074.500.700 D08.811.277.656.300.048.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pepsin A".
Below are MeSH descriptors whose meaning is more specific than "Pepsin A".
This graph shows the total number of publications written about "Pepsin A" by people in this website by year, and whether "Pepsin A" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pepsin A" by people in Profiles.
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Solution structure of a sponge-derived cystine knot peptide and its notable stability. J Nat Prod. 2014 Feb 28; 77(2):304-10.
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Texas 3-step decellularization protocol: looking at the cardiac extracellular matrix. J Proteomics. 2013 Jun 28; 86:43-52.
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Review article: reflux and its consequences--the laryngeal, pulmonary and oesophageal manifestations. Conference held in conjunction with the 9th International Symposium on Human Pepsin (ISHP) Kingston-upon-Hull, UK, 21-23 April 2010. Aliment Pharmacol Ther. 2011 Apr; 33 Suppl 1:1-71.
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Binding site on human immunoglobulin G for the affinity ligand HWRGWV. J Mol Recognit. 2010 May-Jun; 23(3):271-82.
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Distinct effects of gonadectomy in male and female mice on collagen fibrillogenesis in the skin. J Dermatol Sci. 2007 Sep; 47(3):217-26.
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Experimental study of acid burden and acute oesophagitis. Br J Surg. 1998 May; 85(5):677-80.
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Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment. J Biol Chem. 1994 Jun 24; 269(25):17043-7.