"beta-Lactamases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
| Descriptor ID |
D001618
|
| MeSH Number(s) |
D08.811.277.087.180
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta-Lactamases".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactamases".
This graph shows the total number of publications written about "beta-Lactamases" by people in this website by year, and whether "beta-Lactamases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Lactamases" by people in Profiles.
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Emergence of multidrug-resistant ST11 blaKPC-2 producing Klebsiella pneumoniae coharboring blaCTX-M and blaSHV in Pakistan. J Infect Dev Ctries. 2023 02 28; 17(2):210-217.
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Whole-genome sequencing enhances existing pathogen and antimicrobial-resistance surveillance schemes within a neonatal unit. Microb Genom. 2022 06; 8(6).
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Phenotypic and Genotypic Characterization of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae ST17-KL38 Clinical Isolate Harboring the Carbapenemase IMP-4. Microbiol Spectr. 2022 04 27; 10(2):e0213421.
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Alcaligenes faecalis metallo-?-lactamase in extensively drug-resistant Pseudomonas aeruginosa isolates. Clin Microbiol Infect. 2022 Jun; 28(6):880.e1-880.e8.
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Transferable Acinetobacter baumannii plasmid pDETAB2 encodes OXA-58 and NDM-1 and represents a new class of antibiotic resistance plasmids. J Antimicrob Chemother. 2021 04 13; 76(5):1130-1134.
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Emergence of carbapenem-resistant Klebsiella pneumoniae harbouring blaOXA-48-like genes in China. J Med Microbiol. 2021 Mar; 70(3).
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Cointegration as a mechanism for the evolution of a KPC-producing multidrug resistance plasmid in Proteus mirabilis. Emerg Microbes Infect. 2020 Dec; 9(1):1206-1218.
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A Synthetic Dual Drug Sideromycin Induces Gram-Negative Bacteria To Commit Suicide with a Gram-Positive Antibiotic. J Med Chem. 2018 05 10; 61(9):3845-3854.
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Emergence of Ceftolozane-Tazobactam-Resistant Pseudomonas aeruginosa during Treatment Is Mediated by a Single AmpC Structural Mutation. Antimicrob Agents Chemother. 2017 12; 61(12).
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Methodology for Monobactam Diversification: Syntheses and Studies of 4-Thiomethyl Substituted ?-Lactams with Activity against Gram-Negative Bacteria, Including Carbapenemase Producing Acinetobacter baumannii. J Med Chem. 2017 11 09; 60(21):8933-8944.