Catalin F. Baicu

Title
InstitutionMedical University of South Carolina
DepartmentMedicine
AddressP.O. Box MSC 773
324
Thurmond Gazes - 30 Courtenay Drive
Phone843-789-6849
Fax843-876-5068
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Coeyman SJ, Zhang Y, Baicu CF, Zile MR, Bradshaw AD, Richardson WJ. In vitro bioreactor for mechanical control and characterization of tissue constructs. J Biomech. 2023 01; 147:111458. PMID: 36682211; PMCID: PMC9946176.
      Citations:    Fields:    Translation:AnimalsCells
    2. Neff LS, Zhang Y, Van Laer AO, Baicu CF, Karavan M, Zile MR, Bradshaw AD, Neff LS, Zhang Y, Van Laer AO, Baicu CF, Karavan M, Zile MR, Bradshaw AD. Mechanisms that limit regression of myocardial fibrosis following removal of left ventricular pressure overload. Am J Physiol Heart Circ Physiol. 2022 07 01; 323(1):H165-H175. PMID: 35657618; PMCID: PMC9236876.
      Citations: 1     Fields:    Translation:HumansAnimals
    3. Ward M, Yeganegi A, Baicu CF, Bradshaw AD, Spinale FG, Zile MR, Richardson WJ, Ward M, Yeganegi A, Baicu CF, Bradshaw AD, Spinale FG, Zile MR, Richardson WJ. Ensemble machine learning model identifies patients with HFpEF from matrix-related plasma biomarkers. Am J Physiol Heart Circ Physiol. 2022 05 01; 322(5):H798-H805. PMID: 35275763; PMCID: PMC8993521.
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    4. Zhang Y, Van Laer AO, Baicu CF, Neff LS, Hoffman S, Katz MR, Zeigler SM, Zile MR, Bradshaw AD, Zhang Y, Van Laer AO, Baicu CF, Neff LS, Hoffman S, Katz MR, Zeigler SM, Zile MR, Bradshaw AD. Phenotypic characterization of primary cardiac fibroblasts from patients with HFpEF. PLoS One. 2022; 17(1):e0262479. PMID: 35015787; PMCID: PMC8752005.
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    5. Orr RK, Hoehn JL, Col NF, Tomashitis B, Baicu CF, Butschek RA, Jackson GR, Winterfield J, Tedford RJ, Zile MR, Gold MR, Houston BA. Acute Hemodynamic Effects of Cardiac Resynchronization Therapy Versus Alternative Pacing Strategies in Patients With Left Ventricular Assist Devices. J Am Heart Assoc. 2021 03 16; 10(6):e018127. PMID: 33663225; PMCID: PMC8174219.
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    6. Badertscher P, Gregg D, Baicu CF, Ramakrishnan V, Spinale FG, Zile MR, Gold MR, Badertscher P, Gregg D, Baicu CF, Ramakrishnan V, Spinale FG, Zile MR, Gold MR. Racial difference in atrial size and extracellular matrix homeostatic response to hypertension: Is this a potential mechanism of reduced atrial fibrillation in African Americans? Heart Rhythm O2. 2021 Feb; 2(1):37-45. PMID: 34113903; PMCID: PMC8183868.
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    7. Gan P, Baicu C, Watanabe H, Wang K, Tao G, Judge DP, Zile MR, Makita T, Mukherjee R, Sucov HM, Gan P, Baicu C, Watanabe H, Wang K, Tao G, Judge DP, Zile MR, Makita T, Mukherjee R, Sucov HM. The prevalent I686T human variant and loss-of-function mutations in the cardiomyocyte-specific kinase gene TNNI3K cause adverse contractility and concentric remodeling in mice. Hum Mol Genet. 2021 01 06; 29(21):3504-3515. PMID: 33084860; PMCID: PMC7788294.
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    8. Orr RK, Hoehn JL, Col NF, Riley HJ, Kelly RR, Van Laer AO, Neff LS, Dasgupta S, Baicu CF, McDonald LT, LaRue AC, Zile MR, Bradshaw AD. SPARC production by bone marrow-derived cells contributes to myocardial fibrosis in pressure overload. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H604-H612. PMID: 33306449; PMCID: PMC8082795.
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    9. Zile MR, Sharma V, Baicu CF, Koehler J, Tang AS, Zile MR, Sharma V, Baicu CF, Koehler J, Tang AS. Prediction of heart failure hospitalizations based on the direct measurement of intrathoracic impedance. ESC Heart Fail. 2020 10; 7(5):3040-3048. PMID: 32790059; PMCID: PMC7524260.
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    10. O'Brien M, Baicu CF, Van Laer AO, Zhang Y, McDonald LT, LaRue AC, Zile MR, Bradshaw AD, O'Brien M, Baicu CF, Van Laer AO, Zhang Y, McDonald LT, LaRue AC, Zile MR, Bradshaw AD. Pressure overload generates a cardiac-specific profile of inflammatory mediators. Am J Physiol Heart Circ Physiol. 2020 08 01; 319(2):H331-H340. PMID: 32589444; PMCID: PMC7473927.
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    11. Lindsey ML, Deleon-Pennell KY, Bradshaw AD, Larue RAC, Anderson DR, Thiele GM, Baicu CF, Jones JA, Menick DR, Zile MR, Spinale FG, Lindsey ML, Deleon-Pennell KY, Bradshaw AD, Larue RAC, Anderson DR, Thiele GM, Baicu CF, Jones JA, Menick DR, Zile MR, Spinale FG. Focusing Heart Failure Research on Myocardial Fibrosis to Prioritize Translation. J Card Fail. 2020 Oct; 26(10):876-884. PMID: 32446948; PMCID: PMC7584737.
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    12. Zile MR, Baicu CF, Tedford RJ, Zile MR, Baicu CF, Tedford RJ. Repetitive Acute Hemodynamic Load: Progression From Systolic Decompensation to Cellular/Extracellular Compensation to Diastolic Decompensation. JACC Basic Transl Sci. 2019 Aug; 4(4):542-545. PMID: 31468009; PMCID: PMC6712276.
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    13. Yuan C, Wang Z, Borg TK, Ye T, Baicu C, Bradshaw A, Zile M, Runyan RB, Shao Y, Gao BZ, Yuan C, Wang Z, Borg TK, Ye T, Baicu C, Bradshaw A, Zile M, Runyan RB, Shao Y, Gao BZ. Changes in the crystallographic structures of cardiac myosin filaments detected by polarization-dependent second harmonic generation microscopy. Biomed Opt Express. 2019 Jul 01; 10(7):3183-3195. PMID: 31360597; PMCID: PMC6640825.
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    14. Arif E, Solanki AK, Srivastava P, Rahman B, Fitzgibbon WR, Deng P, Budisavljevic MN, Baicu CF, Zile MR, Megyesi J, Janech MG, Kwon SH, Collier J, Schnellmann RG, Nihalani D, Arif E, Solanki AK, Srivastava P, Rahman B, Fitzgibbon WR, Deng P, Budisavljevic MN, Baicu CF, Zile MR, Megyesi J, Janech MG, Kwon SH, Collier J, Schnellmann RG, Nihalani D. Mitochondrial biogenesis induced by the ?2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury. Kidney Int. 2019 09; 96(3):656-673. PMID: 31262488; PMCID: PMC6708766.
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    15. Chinnakkannu P, Reese C, Gaspar JA, Panneerselvam S, Pleasant-Jenkins D, Mukherjee R, Baicu C, Tourkina E, Hoffman S, Kuppuswamy D, Chinnakkannu P, Reese C, Gaspar JA, Panneerselvam S, Pleasant-Jenkins D, Mukherjee R, Baicu C, Tourkina E, Hoffman S, Kuppuswamy D. Suppression of angiotensin II-induced pathological changes in heart and kidney by the caveolin-1 scaffolding domain peptide. PLoS One. 2018; 13(12):e0207844. PMID: 30576317; PMCID: PMC6303044.
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    16. Orr RK, Hoehn JL, Col NF, McDonald LT, Zile MR, Zhang Y, Van Laer AO, Baicu CF, Stroud RE, Jones JA, LaRue AC, Bradshaw AD. Increased macrophage-derived SPARC precedes collagen deposition in myocardial fibrosis. Am J Physiol Heart Circ Physiol. 2018 07 01; 315(1):H92-H100. PMID: 29522370; PMCID: PMC6087775.
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    17. Fitzgibbon WR, Dang Y, Bunni MA, Baicu CF, Zile MR, Mullick AE, Saigusa T, Fitzgibbon WR, Dang Y, Bunni MA, Baicu CF, Zile MR, Mullick AE, Saigusa T. Attenuation of accelerated renal cystogenesis in Pkd1 mice by renin-angiotensin system blockade. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F210-F218. PMID: 29021226; PMCID: PMC5866454.
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    18. Taylor GJ, Lee DM, Baicu CF, Zile MR, Taylor GJ, Lee DM, Baicu CF, Zile MR. Palliative Care for Advanced Heart Failure in a Department of Veterans Affairs Regional Hospice Program: Patient Selection, a Treatment Protocol, and Clinical Course. J Palliat Med. 2017 10; 20(10):1068-1073. PMID: 28530501; PMCID: PMC5915223.
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    19. Zile MR, Bennett TD, El Hajj S, Kueffer FJ, Baicu CF, Abraham WT, Bourge RC, Warner Stevenson L, Zile MR, Bennett TD, El Hajj S, Kueffer FJ, Baicu CF, Abraham WT, Bourge RC, Warner Stevenson L. Intracardiac Pressures Measured Using an Implantable Hemodynamic Monitor: Relationship to Mortality in Patients With Chronic Heart Failure. Circ Heart Fail. 2017 Jan; 10(1). PMID: 28062538.
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    20. Toba H, de Castro Brás LE, Baicu CF, Zile MR, Lindsey ML, Bradshaw AD, Toba H, de Castro Br?s LE, Baicu CF, Zile MR, Lindsey ML, Bradshaw AD. Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium. Am J Physiol Endocrinol Metab. 2016 06 01; 310(11):E1027-35. PMID: 27143554; PMCID: PMC4935141.
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    21. Novgorodov SA, Riley CL, Yu J, Keffler JA, Clarke CJ, Van Laer AO, Baicu CF, Zile MR, Gudz TI, Novgorodov SA, Riley CL, Yu J, Keffler JA, Clarke CJ, Van Laer AO, Baicu CF, Zile MR, Gudz TI. Lactosylceramide contributes to mitochondrial dysfunction in diabetes. J Lipid Res. 2016 Apr; 57(4):546-62. PMID: 26900161; PMCID: PMC4808764.
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    22. Zile MR, Jhund PS, Baicu CF, Claggett BL, Pieske B, Voors AA, Prescott MF, Shi V, Lefkowitz M, McMurray JJ, Solomon SD, Zile MR, Jhund PS, Baicu CF, Claggett BL, Pieske B, Voors AA, Prescott MF, Shi V, Lefkowitz M, McMurray JJ, Solomon SD, Prospective Comparison of ARNI With ARB on Management of Heart Failure With Preserved Ejection Fract. Plasma Biomarkers Reflecting Profibrotic Processes in Heart Failure With a Preserved Ejection Fraction: Data From the Prospective Comparison of ARNI With ARB on Management of Heart Failure With Preserved Ejection Fraction Study. Circ Heart Fail. 2016 Jan; 9(1). PMID: 26754625; PMCID: PMC5485256.
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    23. Zile MR, Sharma V, Johnson JW, Warman EN, Baicu CF, Bennett TD, Zile MR, Sharma V, Johnson JW, Warman EN, Baicu CF, Bennett TD. Prediction of All-Cause Mortality Based on the Direct Measurement of Intrathoracic Impedance. Circ Heart Fail. 2016 Jan; 9(1):e002543. PMID: 26699393; PMCID: PMC4692195.
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    24. Saigusa T, Dang Y, Mullick AE, Yeh ST, Zile MR, Baicu CF, Bell PD, Saigusa T, Dang Y, Mullick AE, Yeh ST, Zile MR, Baicu CF, Bell PD. Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model. FASEB J. 2016 Jan; 30(1):370-9. PMID: 26391272; PMCID: PMC4684522.
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    25. Renaud L, Harris LG, Mani SK, Kasiganesan H, Chou JC, Baicu CF, Van Laer A, Akerman AW, Stroud RE, Jones JA, Zile MR, Menick DR, Renaud L, Harris LG, Mani SK, Kasiganesan H, Chou JC, Baicu CF, Van Laer A, Akerman AW, Stroud RE, Jones JA, Zile MR, Menick DR. HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis. Circ Heart Fail. 2015 Nov; 8(6):1094-104. PMID: 26371176; PMCID: PMC4651803.
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    26. Trombetta-eSilva J, Rosset EA, Hepfer RG, Wright GJ, Baicu C, Yao H, Bradshaw AD, Trombetta-eSilva J, Rosset EA, Hepfer RG, Wright GJ, Baicu C, Yao H, Bradshaw AD. Decreased Mechanical Strength and Collagen Content in SPARC-Null Periodontal Ligament Is Reversed by Inhibition of Transglutaminase Activity. J Bone Miner Res. 2015 Oct; 30(10):1914-24. PMID: 25827352; PMCID: PMC4734383.
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    27. Sas KM, Yin H, Fitzgibbon WR, Baicu CF, Zile MR, Steele SL, Amria M, Saigusa T, Funk J, Bunni MA, Siegal GP, Siroky BJ, Bissler JJ, Bell PD, Sas KM, Yin H, Fitzgibbon WR, Baicu CF, Zile MR, Steele SL, Amria M, Saigusa T, Funk J, Bunni MA, Siegal GP, Siroky BJ, Bissler JJ, Bell PD. Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage. Am J Physiol Renal Physiol. 2015 Jul 01; 309(1):F79-87. PMID: 25904703; PMCID: PMC4490377.
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    28. Toba H, de Castro Brás LE, Baicu CF, Zile MR, Lindsey ML, Bradshaw AD, Toba H, de Castro Br?s LE, Baicu CF, Zile MR, Lindsey ML, Bradshaw AD. Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization. Am J Physiol Cell Physiol. 2015 Jun 15; 308(12):C972-82. PMID: 25877699; PMCID: PMC4469747.
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    29. Cunningham KF, Beeson GC, Beeson CC, Baicu CF, Zile MR, McDermott PJ, Cunningham KF, Beeson GC, Beeson CC, Baicu CF, Zile MR, McDermott PJ. Estrogen-Related Receptor a (ERRa) is required for adaptive increases in PGC-1 isoform expression during electrically stimulated contraction of adult cardiomyocytes in sustained hypoxic conditions. Int J Cardiol. 2015; 187:393-400. PMID: 25841134.
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    30. Medeiros K, O'Connor M, Baicu CF, Fitzgibbons T, Shaw P, Tighe DA, Zile MR, Aurigemma GP, Medeiros K, O'Connor M, Baicu CF, Fitzgibbons T, Shaw P, Tighe DA, Zile MR, Aurigemma GP. Response to letters regarding article, "systolic and diastolic mechanics in stress cardiomyopathy". Circulation. 2015 Mar 10; 131(10):e372. PMID: 25753351.
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    31. Zile MR, Baicu CF, Ikonomidis JS, Stroud RE, Nietert PJ, Bradshaw AD, Slater R, Palmer BM, Van Buren P, Meyer M, Redfield MM, Bull DA, Granzier HL, LeWinter MM, Zile MR, Baicu CF, Ikonomidis JS, Stroud RE, Nietert PJ, Bradshaw AD, Slater R, Palmer BM, Van Buren P, Meyer M, Redfield MM, Bull DA, Granzier HL, LeWinter MM. Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin. Circulation. 2015 Apr 07; 131(14):1247-59. PMID: 25637629; PMCID: PMC4390480.
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    32. Orr RK, Hoehn JL, Col NF, Yarbrough WM, Baicu C, Mukherjee R, Van Laer A, Rivers WT, McKinney RA, Prescott CB, Stroud RE, Freels PD, Zellars KN, Zile MR, Spinale FG. Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H752-61. PMID: 24993046; PMCID: PMC4187400.
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    33. de Castro Brás LE, Toba H, Baicu CF, Zile MR, Weintraub ST, Lindsey ML, Bradshaw AD, de Castro Br?s LE, Toba H, Baicu CF, Zile MR, Weintraub ST, Lindsey ML, Bradshaw AD. Age and SPARC change the extracellular matrix composition of the left ventricle. Biomed Res Int. 2014; 2014:810562. PMID: 24783223; PMCID: PMC3982264.
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    34. Zile MR, Bourge RC, Redfield MM, Zhou D, Baicu CF, Little WC, Zile MR, Bourge RC, Redfield MM, Zhou D, Baicu CF, Little WC. Randomized, double-blind, placebo-controlled study of sitaxsentan to improve impaired exercise tolerance in patients with heart failure and a preserved ejection fraction. JACC Heart Fail. 2014 Apr; 2(2):123-30. PMID: 24720918.
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    35. Medeiros K, O'Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA, Zile MR, Aurigemma GP, Medeiros K, O'Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA, Zile MR, Aurigemma GP. Systolic and diastolic mechanics in stress cardiomyopathy. Circulation. 2014 Apr 22; 129(16):1659-67. PMID: 24503950.
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    36. Zile MR, Baicu CF, Stroud RE, Van Laer AO, Jones JA, Patel R, Mukherjee R, Spinale FG, Zile MR, Baicu CF, Stroud RE, Van Laer AO, Jones JA, Patel R, Mukherjee R, Spinale FG. Mechanistic relationship between membrane type-1 matrix metalloproteinase and the myocardial response to pressure overload. Circ Heart Fail. 2014 Mar 01; 7(2):340-50. PMID: 24395927; PMCID: PMC3961496.
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    37. Zile MR, Baicu CF, Zile MR, Baicu CF. Biomarkers of diastolic dysfunction and myocardial fibrosis: application to heart failure with a preserved ejection fraction. J Cardiovasc Transl Res. 2013 Aug; 6(4):501-15. PMID: 23716130.
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    38. Zile MR, Kjellstrom B, Bennett T, Cho Y, Baicu CF, Aaron MF, Abraham WT, Bourge RC, Kueffer FJ, Zile MR, Kjellstrom B, Bennett T, Cho Y, Baicu CF, Aaron MF, Abraham WT, Bourge RC, Kueffer FJ. Effects of exercise on left ventricular systolic and diastolic properties in patients with heart failure and a preserved ejection fraction versus heart failure and a reduced ejection fraction. Circ Heart Fail. 2013 May; 6(3):508-16. PMID: 23515277.
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    39. Russo SB, Baicu CF, Van Laer A, Geng T, Kasiganesan H, Zile MR, Cowart LA, Russo SB, Baicu CF, Van Laer A, Geng T, Kasiganesan H, Zile MR, Cowart LA. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J Clin Invest. 2012 Nov; 122(11):3919-30. PMID: 23023704; PMCID: PMC3484448.
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    40. Baicu CF, Li J, Zhang Y, Kasiganesan H, Cooper G, Zile MR, Bradshaw AD, Baicu CF, Li J, Zhang Y, Kasiganesan H, Cooper G, Zile MR, Bradshaw AD. Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing. Am J Physiol Heart Circ Physiol. 2012 Nov 01; 303(9):H1128-34. PMID: 22942178; PMCID: PMC3517645.
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    41. McDermott PJ, Baicu CF, Wahl SR, Van Laer AO, Zile MR, McDermott PJ, Baicu CF, Wahl SR, Van Laer AO, Zile MR. In vivo measurements of the contributions of protein synthesis and protein degradation in regulating cardiac pressure overload hypertrophy in the mouse. Mol Cell Biochem. 2012 Aug; 367(1-2):205-13. PMID: 22610791.
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    42. Baicu CF, Zhang Y, Van Laer AO, Renaud L, Zile MR, Bradshaw AD, Baicu CF, Zhang Y, Van Laer AO, Renaud L, Zile MR, Bradshaw AD. Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload. Am J Physiol Heart Circ Physiol. 2012 Jul 15; 303(2):H234-40. PMID: 22610170; PMCID: PMC3404697.
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    43. Harris BS, Baicu CF, Haghshenas N, Kasiganesan H, Scholz D, Rackley MS, Miquerol L, Gros D, Mukherjee R, O'Brien TX, Harris BS, Baicu CF, Haghshenas N, Kasiganesan H, Scholz D, Rackley MS, Miquerol L, Gros D, Mukherjee R, O'Brien TX. Remodeling of the peripheral cardiac conduction system in response to pressure overload. Am J Physiol Heart Circ Physiol. 2012 Apr 15; 302(8):H1712-25. PMID: 22307665; PMCID: PMC3330807.
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    44. Zile MR, Baicu CF, Stroud RE, Van Laer A, Arroyo J, Mukherjee R, Jones JA, Spinale FG, Zile MR, Baicu CF, Stroud RE, Van Laer A, Arroyo J, Mukherjee R, Jones JA, Spinale FG. Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis. Am J Physiol Heart Circ Physiol. 2012 Apr 01; 302(7):H1429-37. PMID: 22287584; PMCID: PMC3330784.
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    45. Cheng G, Kasiganesan H, Baicu CF, Wallenborn JG, Kuppuswamy D, Cooper G, Cheng G, Kasiganesan H, Baicu CF, Wallenborn JG, Kuppuswamy D, Cooper G. Cytoskeletal role in protection of the failing heart by ?-adrenergic blockade. Am J Physiol Heart Circ Physiol. 2012 Feb 01; 302(3):H675-87. PMID: 22081703; PMCID: PMC3353781.
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    46. Zile MR, Gottdiener JS, Hetzel SJ, McMurray JJ, Komajda M, McKelvie R, Baicu CF, Massie BM, Carson PE, Zile MR, Gottdiener JS, Hetzel SJ, McMurray JJ, Komajda M, McKelvie R, Baicu CF, Massie BM, Carson PE, I-PRESERVE Investigators. Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction. Circulation. 2011 Dec 06; 124(23):2491-501. PMID: 22064591.
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    47. Harston RK, McKillop JC, Moschella PC, Van Laer A, Quinones LS, Baicu CF, Balasubramanian S, Zile MR, Kuppuswamy D, Harston RK, McKillop JC, Moschella PC, Van Laer A, Quinones LS, Baicu CF, Balasubramanian S, Zile MR, Kuppuswamy D. Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium. Am J Physiol Heart Circ Physiol. 2011 May; 300(5):H1696-706. PMID: 21357504; PMCID: PMC3094075.
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    48. Zile MR, Desantis SM, Baicu CF, Stroud RE, Thompson SB, McClure CD, Mehurg SM, Spinale FG, Zile MR, Desantis SM, Baicu CF, Stroud RE, Thompson SB, McClure CD, Mehurg SM, Spinale FG. Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure. Circ Heart Fail. 2011 May; 4(3):246-56. PMID: 21350055; PMCID: PMC4071931.
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    49. Chinnakkannu P, Samanna V, Cheng G, Ablonczy Z, Baicu CF, Bethard JR, Menick DR, Kuppuswamy D, Cooper G, Chinnakkannu P, Samanna V, Cheng G, Ablonczy Z, Baicu CF, Bethard JR, Menick DR, Kuppuswamy D, Cooper G. Site-specific microtubule-associated protein 4 dephosphorylation causes microtubule network densification in pressure overload cardiac hypertrophy. J Biol Chem. 2010 Jul 09; 285(28):21837-48. PMID: 20436166; PMCID: PMC2898445.
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    50. Bradshaw AD, Baicu CF, Rentz TJ, Van Laer AO, Bonnema DD, Zile MR, Bradshaw AD, Baicu CF, Rentz TJ, Van Laer AO, Bonnema DD, Zile MR. Age-dependent alterations in fibrillar collagen content and myocardial diastolic function: role of SPARC in post-synthetic procollagen processing. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H614-22. PMID: 20008277; PMCID: PMC2822576.
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    51. Grant JE, Bradshaw AD, Schwacke JH, Baicu CF, Zile MR, Schey KL, Grant JE, Bradshaw AD, Schwacke JH, Baicu CF, Zile MR, Schey KL. Quantification of protein expression changes in the aging left ventricle of Rattus norvegicus. J Proteome Res. 2009 Sep; 8(9):4252-63. PMID: 19603826; PMCID: PMC2752960.
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    52. Xu T, Baicu C, Aho M, Zile M, Boland T, Xu T, Baicu C, Aho M, Zile M, Boland T. Fabrication and characterization of bio-engineered cardiac pseudo tissues. Biofabrication. 2009 Sep; 1(3):035001. PMID: 20811105; PMCID: PMC4120951.
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    53. McCurdy S, Baicu CF, Heymans S, Bradshaw AD, McCurdy S, Baicu CF, Heymans S, Bradshaw AD. Cardiac extracellular matrix remodeling: fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC). J Mol Cell Cardiol. 2010 Mar; 48(3):544-9. PMID: 19577572; PMCID: PMC2823826.
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    54. Johnston RK, Balasubramanian S, Kasiganesan H, Baicu CF, Zile MR, Kuppuswamy D, Johnston RK, Balasubramanian S, Kasiganesan H, Baicu CF, Zile MR, Kuppuswamy D. Beta3 integrin-mediated ubiquitination activates survival signaling during myocardial hypertrophy. FASEB J. 2009 Aug; 23(8):2759-71. PMID: 19364763; PMCID: PMC2717769.
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    55. Bradshaw AD, Baicu CF, Rentz TJ, Van Laer AO, Boggs J, Lacy JM, Zile MR, Bradshaw AD, Baicu CF, Rentz TJ, Van Laer AO, Boggs J, Lacy JM, Zile MR. Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing. Circulation. 2009 Jan 20; 119(2):269-80. PMID: 19118257; PMCID: PMC2734276.
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    56. Cheng G, Zile MR, Takahashi M, Baicu CF, Bonnema DD, Cabral F, Menick DR, Cooper G, Cheng G, Zile MR, Takahashi M, Baicu CF, Bonnema DD, Cabral F, Menick DR, Cooper G. A direct test of the hypothesis that increased microtubule network density contributes to contractile dysfunction of the hypertrophied heart. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2231-41. PMID: 18344371.
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    57. Scholz D, Baicu CF, Tuxworth WJ, Xu L, Kasiganesan H, Menick DR, Cooper G, Scholz D, Baicu CF, Tuxworth WJ, Xu L, Kasiganesan H, Menick DR, Cooper G. Microtubule-dependent distribution of mRNA in adult cardiocytes. Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3):H1135-44. PMID: 18178719.
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    58. Spruill LS, Baicu CF, Zile MR, McDermott PJ, Spruill LS, Baicu CF, Zile MR, McDermott PJ. Selective translation of mRNAs in the left ventricular myocardium of the mouse in response to acute pressure overload. J Mol Cell Cardiol. 2008 Jan; 44(1):69-75. PMID: 18036610; PMCID: PMC2246077.
      Citations:    
    59. Xu L, Renaud L, Müller JG, Baicu CF, Bonnema DD, Zhou H, Kappler CS, Kubalak SW, Zile MR, Conway SJ, Menick DR, Xu L, Renaud L, M?ller JG, Baicu CF, Bonnema DD, Zhou H, Kappler CS, Kubalak SW, Zile MR, Conway SJ, Menick DR. Regulation of Ncx1 expression. Identification of regulatory elements mediating cardiac-specific expression and up-regulation. J Biol Chem. 2006 Nov 10; 281(45):34430-40. PMID: 16966329; PMCID: PMC3096005.
      Citations:    
    60. Poobalarahi F, Baicu CF, Bradshaw AD, Poobalarahi F, Baicu CF, Bradshaw AD. Cardiac myofibroblasts differentiated in 3D culture exhibit distinct changes in collagen I production, processing, and matrix deposition. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2924-32. PMID: 16891407.
      Citations:    
    61. Baicu CF, Zile MR, Aurigemma GP, Gaasch WH, Baicu CF, Zile MR, Aurigemma GP, Gaasch WH. Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure. Circulation. 2005 May 10; 111(18):2306-12. PMID: 15851588.
      Citations:    
    62. Zile MR, Baicu CF, Bonnema DD, Zile MR, Baicu CF, Bonnema DD. Diastolic heart failure: definitions and terminology. Prog Cardiovasc Dis. 2005 Mar-Apr; 47(5):307-13. PMID: 16003645.
      Citations:    
    63. Zile MR, Baicu CF, Gaasch WH, Zile MR, Baicu CF, Gaasch WH. Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med. 2004 May 06; 350(19):1953-9. PMID: 15128895.
      Citations:    
    64. Yost MJ, Baicu CF, Stonerock CE, Goodwin RL, Price RL, Davis JM, Evans H, Watson PD, Gore CM, Sweet J, Creech L, Zile MR, Terracio L, Yost MJ, Baicu CF, Stonerock CE, Goodwin RL, Price RL, Davis JM, Evans H, Watson PD, Gore CM, Sweet J, Creech L, Zile MR, Terracio L. A novel tubular scaffold for cardiovascular tissue engineering. Tissue Eng. 2004 Jan-Feb; 10(1-2):273-84. PMID: 15009952.
      Citations: 15     Fields:    Translation:Cells
    65. Ishibashi Y, Takahashi M, Isomatsu Y, Qiao F, Iijima Y, Shiraishi H, Simsic JM, Baicu CF, Robbins J, Zile MR, Cooper G, Ishibashi Y, Takahashi M, Isomatsu Y, Qiao F, Iijima Y, Shiraishi H, Simsic JM, Baicu CF, Robbins J, Zile MR, Cooper G. Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes. Am J Physiol Heart Circ Physiol. 2003 Sep; 285(3):H1270-85. PMID: 12750067.
      Citations: 10     Fields:    Translation:AnimalsCells
    66. Baicu CF, Stroud JD, Livesay VA, Hapke E, Holder J, Spinale FG, Zile MR, Baicu CF, Stroud JD, Livesay VA, Hapke E, Holder J, Spinale FG, Zile MR. Changes in extracellular collagen matrix alter myocardial systolic performance. Am J Physiol Heart Circ Physiol. 2003 Jan; 284(1):H122-32. PMID: 12485818.
      Citations: 46     Fields:    Translation:AnimalsCells
    67. Stroud JD, Baicu CF, Barnes MA, Spinale FG, Zile MR, Stroud JD, Baicu CF, Barnes MA, Spinale FG, Zile MR. Viscoelastic properties of pressure overload hypertrophied myocardium: effect of serine protease treatment. Am J Physiol Heart Circ Physiol. 2002 Jun; 282(6):H2324-35. PMID: 12003843.
      Citations: 21     Fields:    Translation:AnimalsCells
    68. Harris TS, Baicu CF, Conrad CH, Koide M, Buckley JM, Barnes M, Cooper G, Zile MR, Harris TS, Baicu CF, Conrad CH, Koide M, Buckley JM, Barnes M, Cooper G, Zile MR. Constitutive properties of hypertrophied myocardium: cellular contribution to changes in myocardial stiffness. Am J Physiol Heart Circ Physiol. 2002 Jun; 282(6):H2173-82. PMID: 12003826.
      Citations: 12     Fields:    Translation:AnimalsCells
    69. Nagai T, Laser M, Baicu CF, Zile MR, Cooper G, Kuppuswamy D, Nagai T, Laser M, Baicu CF, Zile MR, Cooper G, Kuppuswamy D. Beta3-integrin-mediated focal adhesion complex formation: adult cardiocytes embedded in three-dimensional polymer matrices. Am J Cardiol. 1999 Jun 17; 83(12A):38H-43H. PMID: 10750585.
      Citations: 7     Fields:    Translation:AnimalsCells
    70. Zile MR, Cowles MK, Buckley JM, Richardson K, Cowles BA, Baicu CF, Cooper G IV, Gharpuray V, Zile MR, Cowles MK, Buckley JM, Richardson K, Cowles BA, Baicu CF, Cooper G IV, Gharpuray V. Gel stretch method: a new method to measure constitutive properties of cardiac muscle cells. Am J Physiol. 1998 Jun; 274(6 Pt 2):H2188-202. PMID: 9841544.
      Citations: 6     Fields:    Translation:Animals
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