Glenn Prazere Lobo

Title
InstitutionMedical University of South Carolina
DepartmentNephrology
AddressP.O. Box MSC 629
Drug Discovery Building, Office 513
Drug Discovery Building - 70 President St.
Phone843-876-2371
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kondkar AA, Sultan T, Azad TA, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA. Lack of Association of Polymorphism Located Upstream of ABCA1 (rs2472493), in FNDC3B (rs7636836), and Near ANKRD55-MAP3K1 Genes (rs61275591) in Primary Open-Angle Glaucoma Patients of Saudi Origin. Genes (Basel). 2023 Mar 13; 14(3). PMID: 36980976.
      Citations:    Fields:    Translation:Humans
    2. Radhakrishnan R, Leung M, Solanki AK, Lobo GP. Mapping of the extracellular RBP4 ligand binding domain on the RBPR2 receptor for Vitamin A transport. Front Cell Dev Biol. 2023; 11:1105657. PMID: 36910150; PMCID: PMC9992173.
      Citations:    
    3. Radhakrishnan R, Leung M, Roehrich H, Walterhouse S, Kondkar AA, Fitzgibbon W, Biswal MR, Lobo GP, Radhakrishnan R, Leung M, Roehrich H, Walterhouse S, Kondkar AA, Fitzgibbon W, Biswal MR, Lobo GP. Mice Lacking the Systemic Vitamin A Receptor RBPR2 Show Decreased Ocular Retinoids and Loss of Visual Function. Nutrients. 2022 Jun 08; 14(12). PMID: 35745101; PMCID: PMC9231411.
      Citations: 1     Fields:    Translation:Animals
    4. Kondkar AA, Sultan T, Azad TA, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA, Kondkar AA, Sultan T, Azad TA, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA. Evaluation of ABCA1 and FNDC3B Gene Polymorphisms Associated With Pseudoexfoliation Glaucoma and Primary Angle-Closure Glaucoma in a Saudi Cohort. Front Genet. 2022; 13:877174. PMID: 35719397; PMCID: PMC9198278.
      Citations: 1     
    5. Radhakrishnan R, Dronamraju VR, Leung M, Gruesen A, Solanki AK, Walterhouse S, Roehrich H, Song G, da Costa Monsanto R, Cureoglu S, Martin R, Kondkar AA, van Kuijk FJ, Montezuma SR, Knöelker HJ, Hufnagel RB, Lobo GP, Radhakrishnan R, Dronamraju VR, Leung M, Gruesen A, Solanki AK, Walterhouse S, Roehrich H, Song G, da Costa Monsanto R, Cureoglu S, Martin R, Kondkar AA, van Kuijk FJ, Montezuma SR, Kn?elker HJ, Hufnagel RB, Lobo GP. The role of motor proteins in photoreceptor protein transport and visual function. Ophthalmic Genet. 2022 06; 43(3):285-300. PMID: 35470760; PMCID: PMC9451523.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    6. Kondkar AA, Azad TA, Sultan T, Radhakrishnan R, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA, Kondkar AA, Azad TA, Sultan T, Radhakrishnan R, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA. Polymorphism rs3742330 in microRNA Biogenesis Gene DICER1 Is Associated with Pseudoexfoliation Glaucoma in Saudi Cohort. Genes (Basel). 2022 03 10; 13(3). PMID: 35328042; PMCID: PMC8956095.
      Citations:    
    7. Martin Ask N, Leung M, Radhakrishnan R, Lobo GP, Martin Ask N, Leung M, Radhakrishnan R, Lobo GP. Vitamin A Transporters in Visual Function: A Mini Review on Membrane Receptors for Dietary Vitamin A Uptake, Storage, and Transport to the Eye. Nutrients. 2021 Nov 09; 13(11). PMID: 34836244; PMCID: PMC8620617.
      Citations:    
    8. Kondkar AA, Sultan T, Alobaidan AS, Azad TA, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA, Kondkar AA, Sultan T, Alobaidan AS, Azad TA, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA. Association analysis of variants rs35934224 in TXNRD2 and rs6478746 in LMX1B in primary angle-closure and pseudoexfoliation glaucoma. Eur J Ophthalmol. 2022 Jul; 32(4):2249-2258. PMID: 34461764.
      Citations:    
    9. Solanki AK, Arif E, Srivastava P, Furcht CM, Rahman B, Wen P, Singh A, Holzman LB, Fitzgibbon WR, Budisavljevic MN, Lobo GP, Kwon SH, Han Z, Lazzara MJ, Lipschutz JH, Nihalani D, Solanki AK, Arif E, Srivastava P, Furcht CM, Rahman B, Wen P, Singh A, Holzman LB, Fitzgibbon WR, Budisavljevic MN, Lobo GP, Kwon SH, Han Z, Lazzara MJ, Lipschutz JH, Nihalani D. Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair. J Biol Chem. 2021 09; 297(3):101079. PMID: 34391780; PMCID: PMC8429977.
      Citations:    
    10. Kondkar AA, Azad TA, Alobaidan AS, Sultan T, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA, Kondkar AA, Azad TA, Alobaidan AS, Sultan T, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA. Lack of Association Between Polymorphisms in TXNRD2 and LMX1B and Primary Open-Angle Glaucoma in a Saudi Cohort. Front Genet. 2021; 12:690780. PMID: 34408771; PMCID: PMC8365832.
      Citations:    
    11. Solanki AK, Biswal MR, Walterhouse S, Martin R, Kondkar AA, Knölker HJ, Rahman B, Arif E, Husain S, Montezuma SR, Nihalani D, Lobo GP, Solanki AK, Biswal MR, Walterhouse S, Martin R, Kondkar AA, Kn?lker HJ, Rahman B, Arif E, Husain S, Montezuma SR, Nihalani D, Lobo GP. Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function. Cells. 2021 05 26; 10(6). PMID: 34073294; PMCID: PMC8229726.
      Citations:    
    12. Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH, Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10). PMID: 34064901; PMCID: PMC8151988.
      Citations:    
    13. Lobo GP, Biswal MR, Kondkar AA, Lobo GP, Biswal MR, Kondkar AA. Editorial: Molecular Mechanisms of Retinal Cell Degeneration and Regeneration. Front Cell Dev Biol. 2021; 9:667028. PMID: 33748148; PMCID: PMC7973204.
      Citations:    
    14. Khiev D, Mohamed ZA, Vichare R, Paulson R, Bhatia S, Mohapatra S, Lobo GP, Valapala M, Kerur N, Passaglia CL, Mohapatra SS, Biswal MR, Khiev D, Mohamed ZA, Vichare R, Paulson R, Bhatia S, Mohapatra S, Lobo GP, Valapala M, Kerur N, Passaglia CL, Mohapatra SS, Biswal MR. Emerging Nano-Formulations and Nanomedicines Applications for Ocular Drug Delivery. Nanomaterials (Basel). 2021 Jan 12; 11(1). PMID: 33445545; PMCID: PMC7828028.
      Citations:    
    15. Solanki AK, Kondkar AA, Fogerty J, Su Y, Kim SH, Lipschutz JH, Nihalani D, Perkins BD, Lobo GP, Solanki AK, Kondkar AA, Fogerty J, Su Y, Kim SH, Lipschutz JH, Nihalani D, Perkins BD, Lobo GP. A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish. Cells. 2020 04 29; 9(5). PMID: 32365517; PMCID: PMC7290320.
      Citations:    
    16. Fulmer D, Toomer K, Guo L, Moore K, Glover J, Moore R, Stairley R, Lobo G, Zuo X, Dang Y, Su Y, Fogelgren B, Gerard P, Chung D, Heydarpour M, Mukherjee R, Body SC, Norris RA, Lipschutz JH, Fulmer D, Toomer K, Guo L, Moore K, Glover J, Moore R, Stairley R, Lobo G, Zuo X, Dang Y, Su Y, Fogelgren B, Gerard P, Chung D, Heydarpour M, Mukherjee R, Body SC, Norris RA, Lipschutz JH. Defects in the Exocyst-Cilia Machinery Cause Bicuspid Aortic Valve Disease and Aortic Stenosis. Circulation. 2019 10 15; 140(16):1331-1341. PMID: 31387361; PMCID: PMC6989054.
      Citations:    
    17. Zuo X, Lobo G, Fulmer D, Guo L, Dang Y, Su Y, Ilatovskaya DV, Nihalani D, Rohrer B, Body SC, Norris RA, Lipschutz JH, Zuo X, Lobo G, Fulmer D, Guo L, Dang Y, Su Y, Ilatovskaya DV, Nihalani D, Rohrer B, Body SC, Norris RA, Lipschutz JH. The exocyst acting through the primary cilium is necessary for renal ciliogenesis, cystogenesis, and tubulogenesis. J Biol Chem. 2019 04 26; 294(17):6710-6718. PMID: 30824539; PMCID: PMC6497951.
      Citations:    
    18. Lobo GP, Pauer G, Lipschutz JH, Hagstrom SA, Lobo GP, Pauer G, Lipschutz JH, Hagstrom SA. The Retinol-Binding Protein Receptor 2 (Rbpr2) Is Required for Photoreceptor Survival and Visual Function in the Zebrafish. Adv Exp Med Biol. 2018; 1074:569-576. PMID: 29721989.
      Citations:    
    19. Shi Y, Su Y, Lipschutz JH, Lobo GP, Shi Y, Su Y, Lipschutz JH, Lobo GP. Zebrafish as models to study ciliopathies of the eye and kidney. Clin Nephrol Res. 2017 Dec; 1(1):6-9. PMID: 29553143; PMCID: PMC5851006.
      Citations:    
    20. Shi Y, Obert E, Rahman B, Rohrer B, Lobo GP, Shi Y, Obert E, Rahman B, Rohrer B, Lobo GP. The Retinol Binding Protein Receptor 2 (Rbpr2) is required for Photoreceptor Outer Segment Morphogenesis and Visual Function in Zebrafish. Sci Rep. 2017 11 24; 7(1):16207. PMID: 29176573; PMCID: PMC5701214.
      Citations:    
    21. Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH, Lobo GP, Fulmer D, Guo L, Zuo X, Dang Y, Kim SH, Su Y, George K, Obert E, Fogelgren B, Nihalani D, Norris RA, Rohrer B, Lipschutz JH. The exocyst is required for photoreceptor ciliogenesis and retinal development. J Biol Chem. 2017 09 08; 292(36):14814-14826. PMID: 28729419; PMCID: PMC5592663.
      Citations:    
    22. Daniele LL, Emran F, Lobo GP, Gaivin RJ, Perkins BD, Daniele LL, Emran F, Lobo GP, Gaivin RJ, Perkins BD. Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):2942-54. PMID: 27273592; PMCID: PMC4898200.
      Citations:    
    23. Lobo GP, Au A, Kiser PD, Hagstrom SA, Lobo GP, Au A, Kiser PD, Hagstrom SA. Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration. PLoS One. 2016; 11(3):e0151806. PMID: 26987071; PMCID: PMC4795779.
      Citations:    
    24. Orr RK, Hoehn JL, Col NF, Lobo GP, Ebke LA, Au A, Hagstrom SA. TULP1 Missense Mutations Induces the Endoplasmic Reticulum Unfolded Protein Response Stress Complex (ER-UPR). Adv Exp Med Biol. 2016; 854:223-30. PMID: 26427415.
      Citations:    
    25. Widjaja-Adhi MA, Lobo GP, Golczak M, Von Lintig J, Widjaja-Adhi MA, Lobo GP, Golczak M, Von Lintig J. A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption. Hum Mol Genet. 2015 Jun 01; 24(11):3206-19. PMID: 25701869; PMCID: PMC4424956.
      Citations:    
    26. Levi L, Lobo G, Doud MK, von Lintig J, Seachrist D, Tochtrop GP, Noy N, Levi L, Lobo G, Doud MK, von Lintig J, Seachrist D, Tochtrop GP, Noy N. Genetic ablation of the fatty acid-binding protein FABP5 suppresses HER2-induced mammary tumorigenesis. Cancer Res. 2013 Aug 01; 73(15):4770-80. PMID: 23722546; PMCID: PMC4082958.
      Citations:    
    27. Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J, Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J. Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX. J Biol Chem. 2013 Mar 29; 288(13):9017-27. PMID: 23393141; PMCID: PMC3610974.
      Citations:    
    28. Lobo GP, Isken A, Hoff S, Babino D, von Lintig J, Lobo GP, Isken A, Hoff S, Babino D, von Lintig J. BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway. Development. 2012 Aug; 139(16):2966-77. PMID: 22764054; PMCID: PMC3403105.
      Citations:    
    29. Lobo GP, Amengual J, Palczewski G, Babino D, von Lintig J, Lobo GP, Amengual J, Palczewski G, Babino D, von Lintig J. Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis. Biochim Biophys Acta. 2012 Jan; 1821(1):78-87. PMID: 21569862; PMCID: PMC3162997.
      Citations:    
    30. Amengual J, Lobo GP, Golczak M, Li HN, Klimova T, Hoppel CL, Wyss A, Palczewski K, von Lintig J, Amengual J, Lobo GP, Golczak M, Li HN, Klimova T, Hoppel CL, Wyss A, Palczewski K, von Lintig J. A mitochondrial enzyme degrades carotenoids and protects against oxidative stress. FASEB J. 2011 Mar; 25(3):948-59. PMID: 21106934; PMCID: PMC3042841.
      Citations:    
    31. Lobo GP, Amengual J, Li HN, Golczak M, Bonet ML, Palczewski K, von Lintig J, Lobo GP, Amengual J, Li HN, Golczak M, Bonet ML, Palczewski K, von Lintig J. Beta,beta-carotene decreases peroxisome proliferator receptor gamma activity and reduces lipid storage capacity of adipocytes in a beta,beta-carotene oxygenase 1-dependent manner. J Biol Chem. 2010 Sep 03; 285(36):27891-9. PMID: 20573961; PMCID: PMC2934656.
      Citations:    
    32. Lobo GP, Hessel S, Eichinger A, Noy N, Moise AR, Wyss A, Palczewski K, von Lintig J, Lobo GP, Hessel S, Eichinger A, Noy N, Moise AR, Wyss A, Palczewski K, von Lintig J. ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production. FASEB J. 2010 Jun; 24(6):1656-66. PMID: 20061533; PMCID: PMC2874479.
      Citations:    
    33. Moise AR, Lobo GP, Erokwu B, Wilson DL, Peck D, Alvarez S, Domínguez M, Alvarez R, Flask CA, de Lera AR, von Lintig J, Palczewski K, Moise AR, Lobo GP, Erokwu B, Wilson DL, Peck D, Alvarez S, Dom?nguez M, Alvarez R, Flask CA, de Lera AR, von Lintig J, Palczewski K. Increased adiposity in the retinol saturase-knockout mouse. FASEB J. 2010 Apr; 24(4):1261-70. PMID: 19940255; PMCID: PMC2845435.
      Citations:    
    34. Moise AR, Alvarez S, Domínguez M, Alvarez R, Golczak M, Lobo GP, von Lintig J, de Lera AR, Palczewski K, Moise AR, Alvarez S, Dom?nguez M, Alvarez R, Golczak M, Lobo GP, von Lintig J, de Lera AR, Palczewski K. Activation of retinoic acid receptors by dihydroretinoids. Mol Pharmacol. 2009 Dec; 76(6):1228-37. PMID: 19770350; PMCID: PMC2784734.
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    35. Lobo GP, Waite KA, Planchon SM, Romigh T, Nassif NT, Eng C, Lobo GP, Waite KA, Planchon SM, Romigh T, Nassif NT, Eng C. Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. Hum Mol Genet. 2009 Aug 01; 18(15):2851-62. PMID: 19457929; PMCID: PMC2706686.
      Citations:    
    36. Ni Y, Zbuk KM, Sadler T, Patocs A, Lobo G, Edelman E, Platzer P, Orloff MS, Waite KA, Eng C, Ni Y, Zbuk KM, Sadler T, Patocs A, Lobo G, Edelman E, Platzer P, Orloff MS, Waite KA, Eng C. Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes. Am J Hum Genet. 2008 Aug; 83(2):261-8. PMID: 18678321; PMCID: PMC2495063.
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    37. Lobo GP, Waite KA, Planchon SM, Romigh T, Houghton JA, Eng C, Lobo GP, Waite KA, Planchon SM, Romigh T, Houghton JA, Eng C. ATP modulates PTEN subcellular localization in multiple cancer cell lines. Hum Mol Genet. 2008 Sep 15; 17(18):2877-85. PMID: 18579579; PMCID: PMC2525500.
      Citations:    
    38. Nassif NT, Lobo GP, Wu X, Henderson CJ, Morrison CD, Eng C, Jalaludin B, Segelov E, Nassif NT, Lobo GP, Wu X, Henderson CJ, Morrison CD, Eng C, Jalaludin B, Segelov E. PTEN mutations are common in sporadic microsatellite stable colorectal cancer. Oncogene. 2004 Jan 15; 23(2):617-28. PMID: 14724591.
      Citations: 55     Fields:    Translation:HumansCells
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