• Home
  • About
    • Overview
    • Sharing Data
    • ORCID
  • Help
  • History (33)
    • Polymethacrylic Acids
    • IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
    • Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial.
    • Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
    • The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    • See All 33 Pages
  • search
    • Find People
    • Find Everything
Login to edit your profile (add a photo, awards, links to other websites, etc.)
  • Edit My Profile
  • My Person List (0)

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med. 2003 Feb; 9(2):220-4.

View in: PubMed

subject areas
  • Animals
  • Base Sequence
  • Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System
  • DNA Primers
  • DNA-Binding Proteins
  • Electrophoretic Mobility Shift Assay
  • Enhancer Elements, Genetic
  • Enzyme Induction
  • Hepatocyte Nuclear Factor 4
  • Humans
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Phosphoproteins
  • Receptors, Cytoplasmic and Nuclear
  • Receptors, Steroid
  • Transcription Factors
  • Tumor Cells, Cultured
  • Xenobiotics

authors with profiles
  • Stephen Alexander Duncan