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Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.

Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish. Dis Model Mech. 2013 Jul; 6(4):925-33.

View in: PubMed

subject areas
  • Abdominal Neoplasms
  • Alleles
  • Animals
  • Blood Vessels
  • Cell Transformation, Neoplastic
  • Gene Silencing
  • Heterozygote
  • Intracellular Signaling Peptides and Proteins
  • Mechanistic Target of Rapamycin Complex 1
  • Mechanistic Target of Rapamycin Complex 2
  • Multiprotein Complexes
  • Mutation
  • Neovascularization, Pathologic
  • Proto-Oncogene Proteins c-akt
  • Signal Transduction
  • Sirolimus
  • TOR Serine-Threonine Kinases
  • Tumor Suppressor Protein p53
  • Tumor Suppressor Proteins
  • Up-Regulation
  • Vascular Endothelial Growth Factor A
  • Zebrafish
  • Zebrafish Proteins

authors with profiles
  • Seok-hyung Kim