Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR.

Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May; 16(3):371-379.

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subject areas

Adult
Aldehyde Oxidoreductases
Aminophenols
Aminopyridines
Benzodioxoles
Biological Availability
Biphenyl Compounds
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Cytochrome P-450 CYP3A Inducers
Dose-Response Relationship, Drug
Drug Combinations
Drug Interactions
Drug Monitoring
Female
Humans
Male
Membrane Transport Modulators
Mutation
Pharmacogenetics
Quinolones
Rifampin
Treatment Outcome

authors with profiles

Patrick A. Flume