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The mechanism of action of estramustine.
Estramustine binds a MAP-1-like protein to inhibit microtubule assembly in vitro and disrupt microtubule organization in DU 145 cells.
Resistance to the antimitotic drug estramustine is distinct from the multidrug resistant phenotype.
Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program.
Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation.
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Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation.
Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. Br J Cancer. 2004 Jun 14; 90(12):2411-7.
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PubMed
subject areas
Antineoplastic Agents
ATP-Binding Cassette Transporters
Carcinoma, Small Cell
Drug Resistance, Neoplasm
Flow Cytometry
Gene Expression Profiling
Humans
Immunohistochemistry
Lung Neoplasms
Mitoxantrone
Nucleic Acid Hybridization
Reverse Transcriptase Polymerase Chain Reaction
Tumor Cells, Cultured
Up-Regulation
authors with profiles
Kenneth D. Tew