Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model.

Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model. Immunology. 2018 07; 154(3):434-451.

View in: PubMed

subject areas

Adenosine Triphosphate
Aminoimidazole Carboxamide
AMP-Activated Protein Kinases
Animals
Biomarkers
Cell Line
Cytokines
Disease Models, Animal
Encephalomyelitis, Autoimmune, Experimental
Female
Gene Expression
Humans
Lovastatin
Mice
Mitochondria
Peroxisomes
rhoA GTP-Binding Protein
rho-Associated Kinases
Ribonucleotides
Spinal Cord

authors with profiles

Inderjit Singh
Devadoss J Samuvel
Avtar K. Singh
Je-Seong Won