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Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8+ T Cells.

Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8+ T Cells. Cancer Immunol Res. 2019 03; 7(3):476-486.

View in: PubMed

subject areas
  • Animals
  • CD8-Positive T-Lymphocytes
  • eIF-2 Kinase
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Stress
  • Gene Knockout Techniques
  • Humans
  • Immunologic Memory
  • Immunotherapy
  • Lymphocytes, Tumor-Infiltrating
  • Mice
  • Mitochondria
  • Oxidoreductases
  • Programmed Cell Death 1 Receptor
  • Reactive Oxygen Species
  • Sarcoma
  • Signal Transduction

authors with profiles
  • Zeke Jonathan Walton
  • Jessica E Thaxton
  • Lee R Leddy