David Priest to Folic Acid Antagonists
This is a "connection" page, showing publications David Priest has written about Folic Acid Antagonists.
Connection Strength
0.681
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Accumulation of plasma reduced folates after folic acid administration. Semin Oncol. 1999 Apr; 26(2 Suppl 6):38-41.
Score: 0.163
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The role of cellular folates in the enhancement of activity of the thymidylate synthase inhibitor 10-propargyl-5,8-dideazafolate against hepatoma cells in vitro by inhibitors of dihydrofolate reductase. J Biol Chem. 1989 Jun 25; 264(18):10685-92.
Score: 0.083
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The enhancement of the activity of 10-propargyl-5,8-dideazafolate and 5,10-dideazatetrahydrofolate by inhibitors of dihydrofolate reductase. Adv Enzyme Regul. 1989; 28:13-21.
Score: 0.080
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Effects of methotrexate on folates in Krebs ascites and L1210 murine leukemia cells. Cancer Lett. 1986 Jan; 30(1):55-9.
Score: 0.065
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Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines. Biochem J. 2002 Nov 01; 367(Pt 3):741-50.
Score: 0.052
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Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. Cancer Res. 2001 May 01; 61(9):3675-81.
Score: 0.047
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Re: Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. J Natl Cancer Inst. 1999 Dec 01; 91(23):2047-50.
Score: 0.043
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Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration. Mol Pharmacol. 1999 Apr; 55(4):761-9.
Score: 0.041
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A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance. J Biol Chem. 1998 Nov 13; 273(46):30189-98.
Score: 0.040
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Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells. Adv Enzyme Regul. 1997; 37:59-76.
Score: 0.035
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Altered transport of folic acid and antifolates through the carrier mediated reduced folate transport system in a human leukemia cell line resistant to (6R) 5,10-dideazatetrahydrofolic acid (DDATHF). Adv Exp Med Biol. 1993; 338:775-8.
Score: 0.026
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Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res. 1995 Feb 01; 55(3):566-73.
Score: 0.008