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    • Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.
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Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.

Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity. Int J Cancer. 2012 Apr 01; 130(7):1660-70.

View in: PubMed

subject areas
  • Adult
  • Anticarcinogenic Agents
  • Apoptosis
  • bcl-2-Associated X Protein
  • Breast Neoplasms
  • Cell Cycle
  • Cell Line, Tumor
  • Cell Movement
  • Cell Survival
  • Cyclin-Dependent Kinase Inhibitor p21
  • DNA Damage
  • DNA Topoisomerases
  • DNA, Superhelical
  • Down-Regulation
  • Epithelial Cells
  • Female
  • Gene Expression Regulation, Neoplastic
  • Humans
  • NF-kappa B
  • Poly(ADP-ribose) Polymerases
  • Quinacrine
  • Topoisomerase Inhibitors
  • Tumor Suppressor Protein p53

authors with profiles
  • Michael Wyatt