The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines.

The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines. Cancer Chemother Pharmacol. 2010 May; 65(6):1067-81.

View in: PubMed

subject areas

Acetyltransferases
Animals
Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Breast Neoplasms
Cell Line
Cell Line, Tumor
Cell Proliferation
Drug Synergism
Female
Fluorouracil
Gene Expression Regulation, Enzymologic
Humans
Mammary Neoplasms, Experimental
Mice
Mice, Inbred BALB C
Mice, Nude
Molecular Structure
Oxidoreductases Acting on CH-NH Group Donors
Paclitaxel
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Spermine
Xenograft Model Antitumor Assays

authors with profiles

Patrick M Woster