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Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.
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Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.
Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12; 52(21):6515-8.
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PubMed
subject areas
Administration, Topical
Animals
Antihypertensive Agents
Glaucoma
Guanidines
In Vitro Techniques
Intraocular Pressure
Lim Kinases
Mice
Nitriles
Ocular Hypertension
Piperazines
Pyrimidines
Pyrroles
Structure-Activity Relationship
Swine
Urea
authors with profiles
Craig E. Crosson