"Lim Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.
| Descriptor ID |
D054461
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.542 D12.644.360.390 D12.776.476.396 D12.776.512.124
|
| Concept/Terms |
Lim Kinases- Lim Kinases
- Kinases, Lim
- LIM Motif-Containing Protein Kinases
- LIM Motif Containing Protein Kinases
- LIM-Kinase
- LIM Kinase
- Kinase, LIM
|
Below are MeSH descriptors whose meaning is more general than "Lim Kinases".
Below are MeSH descriptors whose meaning is more specific than "Lim Kinases".
This graph shows the total number of publications written about "Lim Kinases" by people in this website by year, and whether "Lim Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lim Kinases" by people in Profiles.
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Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 03 04; 9(1):3357.
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Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12; 52(21):6515-8.