C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice.

C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice. Front Immunol. 2020; 11:575154.

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subject areas

Animals
Antirheumatic Agents
Apoptosis
Arthritis, Experimental
Cells, Cultured
Complement Activation
Human Umbilical Vein Endothelial Cells
Humans
Immunoglobulin M
Joints
Mice, Inbred C57BL
Mice, Inbred DBA
Receptors, Complement 3b
Recombinant Fusion Proteins
Single-Chain Antibodies
Synoviocytes
Thymocytes

authors with profiles

Stephen Tomlinson