CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs.
CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs. Front Immunol. 2020; 11:561889.
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Animals
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Antigens, Neoplasm
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CD4 Antigens
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Histocompatibility Antigens Class II
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Hybridomas
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Immunotherapy, Adoptive
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Interleukin-2
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Lymphocyte Activation
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Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
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Mice
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Mice, Inbred C57BL
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Mice, Transgenic
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Models, Immunological
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Receptors, Antigen, T-Cell, alpha-beta
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Signal Transduction
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T-Lymphocytes, Helper-Inducer
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Transduction, Genetic
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Yeasts