"Perforant Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pathway of fibers that originates in the lateral part of the ENTORHINAL CORTEX, perforates the SUBICULUM of the HIPPOCAMPUS, and runs into the stratum moleculare of the hippocampus, where these fibers synapse with others that go to the DENTATE GYRUS where the pathway terminates. It is also known as the perforating fasciculus.
| Descriptor ID |
D019580
|
| MeSH Number(s) |
A08.186.211.464.730 A08.612.600
|
| Concept/Terms |
Perforant Pathway- Perforant Pathway
- Pathway, Perforant
- Pathways, Perforant
- Perforant Pathways
- Perforant Path
- Path, Perforant
- Paths, Perforant
- Perforant Paths
- Perforating Fasciculus
- Fasciculus, Perforating
|
Below are MeSH descriptors whose meaning is more general than "Perforant Pathway".
Below are MeSH descriptors whose meaning is more specific than "Perforant Pathway".
This graph shows the total number of publications written about "Perforant Pathway" by people in this website by year, and whether "Perforant Pathway" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Perforant Pathway" by people in Profiles.
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The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease. Mol Cell Proteomics. 2020 01; 19(1):128-141.
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Deficits in synaptic function occur at medial perforant path-dentate granule cell synapses prior to Schaffer collateral-CA1 pyramidal cell synapses in the novel TgF344-Alzheimer's Disease Rat Model. Neurobiol Dis. 2018 Feb; 110:166-179.
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Increased long-term potentiation at medial-perforant path-dentate granule cell synapses induced by selective inhibition of histone deacetylase 3 requires Fragile X mental retardation protein. Neurobiol Learn Mem. 2014 Oct; 114:193-7.
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Medial perforant path inhibition mediated by mGluR7 is reduced after status epilepticus. J Neurophysiol. 2004 Sep; 92(3):1549-57.