Long-Term Synaptic Depression
"Long-Term Synaptic Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
| Descriptor ID |
D036881
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| MeSH Number(s) |
G11.561.638.355
|
| Concept/Terms |
Long-Term Synaptic Depression- Long-Term Synaptic Depression
- Long Term Synaptic Depression
- Synaptic Depression, Long-Term
- Long-Term Depression, Physiological
- Depression, Physiological Long-Term
- Depressions, Physiological Long-Term
- Long Term Depression, Physiological
- Long-Term Depressions, Physiological
- Physiological Long-Term Depression
- Physiological Long-Term Depressions
- Long-Term Depression, Neurophysiological
- Depression, Neurophysiological Long-Term
- Depressions, Neurophysiological Long-Term
- Long Term Depression, Neurophysiological
- Long-Term Depressions, Neurophysiological
- Neurophysiological Long-Term Depression
- Neurophysiological Long-Term Depressions
- Long-Term Depression, Physiologic
- Long Term Depression, Physiologic
- Physiologic Long-Term Depression
- Long-Term Depression, Neurophysiologic
- Long Term Depression, Neurophysiologic
- Neurophysiologic Long-Term Depression
Depotentiation- Depotentiation
- Homosynaptic Depression
- Depression, Homosynaptic
|
Below are MeSH descriptors whose meaning is more general than "Long-Term Synaptic Depression".
Below are MeSH descriptors whose meaning is more specific than "Long-Term Synaptic Depression".
This graph shows the total number of publications written about "Long-Term Synaptic Depression" by people in this website by year, and whether "Long-Term Synaptic Depression" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Long-Term Synaptic Depression" by people in Profiles.
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The loss of NMDAR-dependent LTD following cannabinoid self-administration is restored by positive allosteric modulation of CB1 receptors. Addict Biol. 2020 11; 25(6):e12843.
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Muscarinic M1 Receptor Modulation of Synaptic Plasticity in Nucleus Accumbens of Wild-Type and Fragile X Mice. ACS Chem Neurosci. 2018 09 19; 9(9):2233-2240.
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Loss of Ethanol Inhibition of N-Methyl-D-Aspartate Receptor-Mediated Currents and Plasticity of Cerebellar Synapses in Mice Expressing the GluN1(F639A) Subunit. Alcohol Clin Exp Res. 2018 Apr; 42(4):698-705.
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Acute Increases in Protein O-GlcNAcylation Dampen Epileptiform Activity in Hippocampus. J Neurosci. 2017 Aug 23; 37(34):8207-8215.
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Addiction-like Synaptic Impairments in Diet-Induced Obesity. Biol Psychiatry. 2017 05 01; 81(9):797-806.
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Failure to Recognize Novelty after Extended Methamphetamine Self-Administration Results from Loss of Long-Term Depression in the Perirhinal Cortex. Neuropsychopharmacology. 2015 Oct; 40(11):2526-35.
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Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene. Addict Biol. 2016 May; 21(3):530-46.
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An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. J Neurophysiol. 2014 Nov 15; 112(10):2388-97.
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O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses. J Neurosci. 2014 Jan 01; 34(1):10-21.
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The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning. Addict Biol. 2014 Jan; 19(1):87-101.