Enzyme-Linked Immunosorbent Assay
"Enzyme-Linked Immunosorbent Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
| Descriptor ID |
D004797
|
| MeSH Number(s) |
E05.478.566.350.170 E05.478.566.380.360 E05.478.583.400.170 E05.601.470.350.170 E05.601.470.380.360
|
| Concept/Terms |
Enzyme-Linked Immunosorbent Assay- Enzyme-Linked Immunosorbent Assay
- Assay, Enzyme-Linked Immunosorbent
- Assays, Enzyme-Linked Immunosorbent
- Enzyme Linked Immunosorbent Assay
- Enzyme-Linked Immunosorbent Assays
- Immunosorbent Assay, Enzyme-Linked
- Immunosorbent Assays, Enzyme-Linked
- ELISA
|
Below are MeSH descriptors whose meaning is more general than "Enzyme-Linked Immunosorbent Assay".
Below are MeSH descriptors whose meaning is more specific than "Enzyme-Linked Immunosorbent Assay".
This graph shows the total number of publications written about "Enzyme-Linked Immunosorbent Assay" by people in this website by year, and whether "Enzyme-Linked Immunosorbent Assay" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 9 | 9 |
| 1995 | 0 | 7 | 7 |
| 1996 | 0 | 6 | 6 |
| 1997 | 0 | 11 | 11 |
| 1998 | 2 | 5 | 7 |
| 1999 | 1 | 7 | 8 |
| 2000 | 0 | 11 | 11 |
| 2001 | 0 | 9 | 9 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 19 | 19 |
| 2004 | 1 | 17 | 18 |
| 2005 | 2 | 14 | 16 |
| 2006 | 2 | 14 | 16 |
| 2007 | 1 | 12 | 13 |
| 2008 | 2 | 10 | 12 |
| 2009 | 2 | 15 | 17 |
| 2010 | 3 | 19 | 22 |
| 2011 | 1 | 22 | 23 |
| 2012 | 1 | 17 | 18 |
| 2013 | 0 | 9 | 9 |
| 2014 | 0 | 15 | 15 |
| 2015 | 2 | 12 | 14 |
| 2016 | 0 | 11 | 11 |
| 2017 | 1 | 5 | 6 |
| 2018 | 0 | 5 | 5 |
| 2019 | 1 | 5 | 6 |
| 2020 | 0 | 5 | 5 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Enzyme-Linked Immunosorbent Assay" by people in Profiles.
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A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples. Nat Commun. 2022 Nov 11; 13(1):6852.
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Simple, Rapid Chemical Labeling and Screening of Antibodies with Luminescent Peptides. ACS Chem Biol. 2022 08 19; 17(8):2179-2187.
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Toward a Point-of-Need Bioluminescence-Based Immunoassay Utilizing a Complete Shelf-Stable Reagent. Anal Chem. 2021 03 30; 93(12):5177-5184.
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Multiplex quantitative detection of SARS-CoV-2 specific IgG and IgM antibodies based on DNA-assisted nanopore sensing. Biosens Bioelectron. 2021 Jun 01; 181:113134.
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Fecal Calprotectin Is Elevated in HIV and Related to Systemic Inflammation. J Acquir Immune Defic Syndr. 2021 02 01; 86(2):231-239.
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Evaluation of Orthogonal Testing Algorithm for Detection of SARS-CoV-2 IgG Antibodies. Clin Chem. 2020 12 01; 66(12):1531-1537.
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Abundance and nuclear antigen reactivity of intestinal and fecal Immunoglobulin A in lupus-prone mice at younger ages correlate with the onset of eventual systemic autoimmunity. Sci Rep. 2020 08 31; 10(1):14258.
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Reproductive Outcomes in Rhesus Macaques (Macaca mulatta) with Naturally-acquired Trypanosoma cruzi Infection. Comp Med. 2020 04 01; 70(2):152-159.
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Immunization Against Oxidized Elastin Exacerbates Structural and Functional Damage in Mouse Model of Smoke-Induced Ocular Injury. Invest Ophthalmol Vis Sci. 2020 03 09; 61(3):45.
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Evidence of vasculature and chondrocyte to osteoblast transdifferentiation in craniofacial synovial joints: Implications for osteoarthritis diagnosis and therapy. FASEB J. 2020 03; 34(3):4445-4461.