"Trimethoprim" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
Descriptor ID |
D014295
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MeSH Number(s) |
D03.383.742.906
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trimethoprim".
Below are MeSH descriptors whose meaning is more specific than "Trimethoprim".
This graph shows the total number of publications written about "Trimethoprim" by people in this website by year, and whether "Trimethoprim" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trimethoprim" by people in Profiles.
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pCERC3 from a commensal ST95 Escherichia coli: A ColV virulence-multiresistance plasmid carrying a sul3-associated class 1 integron. Plasmid. 2016 Mar-May; 84-85:11-9.
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What's eating you? Pediculus humanus (head louse and body louse). Cutis. 1999 May; 63(5):259-64.
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Successful therapy of penicillinase-producing Neisseria gonorrhoeae pharyngeal infection during pregnancy. Obstet Gynecol. 1986 Aug; 68(2):290-1.
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Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. Drug Intell Clin Pharm. 1982 May; 16(5):387-90.
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Parenteral trimethoprim-sulfamethoxazole and carbenicillin as empiric therapy for neutropenic patients with cancer. Rev Infect Dis. 1982 Mar-Apr; 4(2):586-92.
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Carbenicillin-trimethoprim/sulfamethoxazole versus carbenicillin-gentamicin as empiric therapy of infection in granulocytopenic patients. A prospective, randomized, double-blind study. Am J Med. 1980 Jun; 68(6):876-85.
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Trimethoprim-sulfamethoxzole: a rational antibiotic combination with many potential indications. J S C Med Assoc. 1976 Jul; 72(7):264-5.
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[Treatment of chronic pyelonephritis using Bactrim]. Lijec Vjesn. 1972 Nov; 94(11):568-72.